Abstract
To directly address the function of a putative auxin receptor designated ABP1, a reverse genetic approach was taken to identify and characterize ABP1 mutant alleles in Arabidopsis. A homozygous null mutation in ABP1 confers embryo lethality. Null mutant embryos develop normally until the early stages of the globular embryo but are unable to make the transition to a bilaterally symmetrical structure because cells fail to elongate. Cell division was also aberrant both in the suspensor and embryo proper. Antisense suppression of ABP1 in tobacco cells causes slow proliferation and eliminates auxin-induced cell elongation and reduces cell division. The complete lack of auxin-inducible elongation in individual cells confirms the results observed in embryos, indicates a cell autonomous function, and, taken together with biochemical evidence that ABP1 binds auxins, suggests that ABP1 mediates auxin-induced cell elongation and, directly or indirectly, cell division.
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Claims 8
Claim · model-written summary
An ABP1 homozygous null mutation causes embryo lethality.
- Taxon
- Arabidopsis
Arabidopsist0 - Treatment
- homozygous null mutation in ABP1e0
- Gene
- ABP1e0
- Outcome
- embryo lethalitye0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A homozygous null mutation in ABP1 confers embryo lethality.”
t0“Arabidopsis”
Claim · model-written summary
Null mutant embryos develop normally through early globular stages.
- Taxon
- ArabidopsisArabidopsist0
- Material
- Null mutant embryose0
- Outcome
- develop normally until the early stages of the globular embryoe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Null mutant embryos develop normally until the early stages of the globular embryo”
t0“Arabidopsis”
Claim · model-written summary
Null embryos fail to become bilaterally symmetrical because cells do not elongate.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- unable to make the transition to a bilaterally symmetrical structuree0
- Qualifier
- cells fail to elongatee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“unable to make the transition to a bilaterally symmetrical structure because cells fail to elongate.”
t0“Arabidopsis”
Claim · model-written summary
Cell division was aberrant in the suspensor and embryo proper.
- Taxon
- ArabidopsisArabidopsist0
- Organ / stage
- suspensor and embryo propere0
- Outcome
- Cell division was also aberrante0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cell division was also aberrant both in the suspensor and embryo proper.”
t0“Arabidopsis”
Claim · model-written summary
ABP1 antisense suppression slowed tobacco cell proliferation.
- Taxon
- tobacco
Nicotiana tabacume0 - Treatment
- Antisense suppression of ABP1e0
- Gene
- ABP1e0
- Outcome
- proliferatione0
- Direction
- slowe0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Antisense suppression of ABP1 in tobacco cells causes slow proliferation”
Claim · model-written summary
ABP1 antisense suppression eliminated auxin-induced tobacco cell elongation.
- Taxon
- tobaccoNicotiana tabacume0
- Treatment
- Antisense suppression of ABP1e0
- Gene
- ABP1e0
- Outcome
- auxin-induced cell elongatione0
- Direction
- eliminatese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Antisense suppression of ABP1 in tobacco cells causes slow proliferation and eliminates auxin-induced cell elongation”
Claim · model-written summary
ABP1 antisense suppression reduced tobacco cell division.
- Taxon
- tobaccoNicotiana tabacume0
- Treatment
- Antisense suppression of ABP1e0
- Gene
- ABP1e0
- Outcome
- cell divisione0
- Direction
- reducese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Antisense suppression of ABP1 in tobacco cells causes slow proliferation and eliminates auxin-induced cell elongation and reduces cell division.”
Claim · model-written summary
The authors infer a cell-autonomous role for ABP1 in auxin-induced elongation and cell division.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- ABP1e0
- Outcome
- auxin-induced cell elongation and, directly or indirectly, cell divisione0
- Qualifier
- cell autonomous functione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“indicates a cell autonomous function, and, taken together with biochemical evidence that ABP1 binds auxins, suggests that ABP1 mediates auxin-induced cell elongation and, directly or indirectly, cell division.”
t0“Arabidopsis”
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See all 9 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.