Abstract
As one of the heavy metal pollutants with strong biological toxicity, cadmium (Cd) is easily absorbed by plant roots, which seriously restricts the growth of plants, causes the quality of agricultural products to decline and threatens human health. Many complex signal transduction pathways are involved in the process of plant response to Cd stress. Among them, plant hormone ethylene is an important signal molecule for plant response to various environmental stresses, and its regulatory mechanism and signal transduction pathway in Cd stress response need to be further clarified. Here, we discovered that Cd stress induced a significant increment in ethylene production in Arabidopsis roots, and the amount of ethylene produced was positively correlated with the inhibition of Arabidopsis root growth and Cd accumulation. Simultaneously, Cd stress stimulated the detoxification mechanism within cells and promoted the expression of METAL TOLERANCE PROTEIN 3 (MTP3), IRON-REGULATED TRANSPORTER2 (IRT2), IRON REGULATED GENE 2 (IREG2) genes implicated in Cd vacuolar compartmentation. However, whether this is associated with ethylene signal transduction remains to be further explored. Further studies have revealed that the Cd induced ethylene burst is attributed to the up-regulation of the expression of 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID SYNTHASE (ACS) genes that mediated by MITONGEN-ACTIVATED PROTEIN KINASE 6 (MAPK6) in Arabidopsis roots, and among them, ACS2 and ACS6, especially ACS2, are involved in MAPK6-induced ethylene production under Cd stress. The results of this study provide new ideas for understanding the signal transduction pathway of plant response to Cd stress.
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Claims 10
Claim · model-written summary
Cd stress significantly increased ethylene production in Arabidopsis roots.
- Taxon
- Arabidopsis
Arabidopsise0 - Organ / stage
- rootse0
- Treatment
- Cd stresse0
- Outcome
- ethylene productione0
- Direction
- incremente0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd stress induced a significant increment in ethylene production in Arabidopsis roots”
Claim · model-written summary
Ethylene production correlated positively with Arabidopsis root growth inhibition.
- Taxon
- ArabidopsisArabidopsise0
- Compound
- ethylenee0
- Outcome
- inhibition of Arabidopsis root growthe0
- Direction
- positively correlatede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the amount of ethylene produced was positively correlated with the inhibition of Arabidopsis root growth and Cd accumulation.”
Claim · model-written summary
Ethylene production correlated positively with Cd accumulation.
- Taxon
- ArabidopsisArabidopsise0
- Compound
- ethylenee0
- Outcome
- Cd accumulatione0
- Direction
- positively correlatede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the amount of ethylene produced was positively correlated with the inhibition of Arabidopsis root growth and Cd accumulation.”
Claim · model-written summary
Cd stress stimulated a cellular detoxification mechanism.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Cd stresse0
- Outcome
- detoxification mechanism within cellse0
- Direction
- stimulatede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd stress stimulated the detoxification mechanism within cells and promoted the expression of METAL TOLERANCE PROTEIN 3 (MTP3), IRON-REGULATED TRANSPORTER2 (IRT2), IRON REGULATED GENE 2 (IREG2) genes implicated in Cd vacuolar compartmentation.”
t0“Arabidopsis thaliana”
Claim · model-written summary
Cd stress promoted MTP3 expression.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Cd stresse0
- Gene
- METAL TOLERANCE PROTEIN 3 (MTP3)e0
- Outcome
- expressione0
- Direction
- promotede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd stress stimulated the detoxification mechanism within cells and promoted the expression of METAL TOLERANCE PROTEIN 3 (MTP3), IRON-REGULATED TRANSPORTER2 (IRT2), IRON REGULATED GENE 2 (IREG2) genes implicated in Cd vacuolar compartmentation.”
t0“Arabidopsis thaliana”
Claim · model-written summary
Cd stress promoted IRT2 expression.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Cd stresse0
- Gene
- IRON-REGULATED TRANSPORTER2 (IRT2)e0
- Outcome
- expressione0
- Direction
- promotede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd stress stimulated the detoxification mechanism within cells and promoted the expression of METAL TOLERANCE PROTEIN 3 (MTP3), IRON-REGULATED TRANSPORTER2 (IRT2), IRON REGULATED GENE 2 (IREG2) genes implicated in Cd vacuolar compartmentation.”
t0“Arabidopsis thaliana”
Claim · model-written summary
Cd stress promoted IREG2 expression.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Cd stresse0
- Gene
- IRON REGULATED GENE 2 (IREG2)e0
- Outcome
- expressione0
- Direction
- promotede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd stress stimulated the detoxification mechanism within cells and promoted the expression of METAL TOLERANCE PROTEIN 3 (MTP3), IRON-REGULATED TRANSPORTER2 (IRT2), IRON REGULATED GENE 2 (IREG2) genes implicated in Cd vacuolar compartmentation.”
t0“Arabidopsis thaliana”
Claim · model-written summary
MAPK6-mediated ACS upregulation was attributed as the cause of the Cd-induced ethylene burst.
- Taxon
- ArabidopsisArabidopsise0
- Organ / stage
- rootse0
- Gene
- 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID SYNTHASE (ACS)e0
- Outcome
- Cd induced ethylene burste0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the Cd induced ethylene burst is attributed to the up-regulation of the expression of 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID SYNTHASE (ACS) genes that mediated by MITONGEN-ACTIVATED PROTEIN KINASE 6 (MAPK6) in Arabidopsis roots”
Claim · model-written summary
ACS2 was involved in MAPK6-induced ethylene production under Cd stress, especially prominently.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Cd stresse0
- Gene
- ACS2e0
- Outcome
- ethylene productione0
- Qualifier
- especially ACS2e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“ACS2 and ACS6, especially ACS2, are involved in MAPK6-induced ethylene production under Cd stress.”
t0“Arabidopsis thaliana”
Claim · model-written summary
ACS6 was involved in MAPK6-induced ethylene production under Cd stress.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Cd stresse0
- Gene
- ACS6e0
- Outcome
- ethylene productione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“ACS2 and ACS6, especially ACS2, are involved in MAPK6-induced ethylene production under Cd stress.”
t0“Arabidopsis thaliana”
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See all 8 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.