Abstract
Abstract Continued climate change impose multiple stressors on crops, including pathogens, salt, and drought, severely impacting agricultural productivity. Innovative solutions are necessary to develop resilient crops. Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility. We show that knockout or silencing of Parakletos enhances resistance to oomycete, fungi, bacteria, salt, and drought, whereas its overexpression reduces resistance. In response to biotic stimuli, Parakletos -overexpressing plants exhibit reduced amplitude of reactive oxygen species and Ca 2+ signalling, and silencing Parakletos does the opposite. Parakletos homologues have been identified in all major crops. Consecutive years of field trials demonstrate that Parakletos deletion enhances resistance to Phytophthora infestans and increases yield. These findings demark a susceptibility gene, which can be exploited to enhance crop resilience towards abiotic and biotic stresses in a low-input agriculture.
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Claims 10
Claim · model-written summary
Parakletos contributes to disease susceptibility in potato.
- Taxon
- potato
Solanum tuberosume1 - Gene
- Parakletose1
- Outcome
- disease susceptibilitye1
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
Claim · model-written summary
Knockout or silencing of Parakletos enhanced resistance of potato to oomycete, fungi and bacteria.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- knockout or silencing of Parakletose2
- Interactor
- oomycetee2pathogen
- Gene
- Parakletose2
- Outcome
- resistance to oomycete, fungi, bacteriae2
- Direction
- enhancese2
- Qualifier
- fungi, bacteriae2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e2“We show that knockout or silencing of Parakletos enhances resistance to oomycete, fungi, bacteria, salt, and drought, whereas its overexpression reduces resistance”
Claim · model-written summary
Knockout or silencing of Parakletos enhanced potato resistance to salt and drought.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- knockout or silencing of Parakletose2
- Gene
- Parakletose2
- Outcome
- resistancee2
- Direction
- enhancese2
- Qualifier
- salt, and droughte2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e2“We show that knockout or silencing of Parakletos enhances resistance to oomycete, fungi, bacteria, salt, and drought, whereas its overexpression reduces resistance”
Claim · model-written summary
Overexpression of Parakletos reduced potato resistance.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- its overexpressione3
- Gene
- Parakletose1
- Outcome
- resistancee3
- Direction
- reducese3
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e3“whereas its overexpression reduces resistance”
Claim · model-written summary
Parakletos-overexpressing potato plants showed reduced amplitude of reactive oxygen species and Ca 2+ signalling in response to biotic stimuli.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- Parakletos -overexpressinge4
- Gene
- Parakletose4
- Outcome
- amplitude of reactive oxygen species and Ca 2+ signallinge4
- Direction
- reducede4
- Qualifier
- In response to biotic stimulie4
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e4“In response to biotic stimuli, Parakletos -overexpressing plants exhibit reduced amplitude of reactive oxygen species and Ca 2+ signalling, and silencing Parakletos does the opposite”
Claim · model-written summary
Silencing Parakletos in potato had the opposite effect on reactive oxygen species and Ca 2+ signalling in response to biotic stimuli.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- silencing Parakletose4
- Gene
- Parakletose4
- Outcome
- reactive oxygen species and Ca 2+ signallinge4
- Direction
- the oppositee4
- Qualifier
- In response to biotic stimulie4
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e4“In response to biotic stimuli, Parakletos -overexpressing plants exhibit reduced amplitude of reactive oxygen species and Ca 2+ signalling, and silencing Parakletos does the opposite”
Claim · model-written summary
Parakletos homologues were identified in all major crops.
- Taxon
- potatoSolanum tuberosume1
- Gene
- Parakletos homologuese5
- Outcome
- identifiede5
- Qualifier
- in all major cropse5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e5“Parakletos homologues have been identified in all major crops”
Claim · model-written summary
Parakletos deletion enhanced potato resistance to Phytophthora infestans in consecutive years of field trials.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- Parakletos deletione6
- Interactor
- Phytophthora infestans
Phytophthora infestanse6pathogen - Gene
- Parakletose6
- Outcome
- resistance to Phytophthora infestanse6
- Direction
- enhancese6
- Setting
- Consecutive years of field trialse6
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e6“Consecutive years of field trials demonstrate that Parakletos deletion enhances resistance to Phytophthora infestans and increases yield”
Claim · model-written summary
Parakletos deletion increased potato yield in consecutive years of field trials.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- Parakletos deletione6
- Outcome
- yielde6
- Direction
- increasese6
- Setting
- Consecutive years of field trialse6
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e6“Consecutive years of field trials demonstrate that Parakletos deletion enhances resistance to Phytophthora infestans and increases yield”
Claim · model-written summary
The Parakletos susceptibility gene can be exploited to enhance potato crop resilience in low-input agriculture.
- Taxon
- potatoSolanum tuberosume1
- Outcome
- enhance crop resiliencee7
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility”
e7“These findings demark a susceptibility gene, which can be exploited to enhance crop resilience towards abiotic and biotic stresses in a low-input agriculture”
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See all 31 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.