Abstract
Cd~(2+) treatment could lead to a significant accumulation of proline,sequential up-regulation of activities of the key enzymes(ornithine-8-aminotansferase,arginase,A'-pyrroline-5-carboxylate synthetase and glutamate dehydrogenase) for proline biosynthesis,and inhibition of activity of the key enzyme proline dehydrogenase for proline degradation in tobacco(Nicotiana tabacum L.) suspension cells.These results indicated that the Cd~(2+) stress-induced proline accumulation in the tobacco cells might be a combined result of the orderly activation of the ornithine pathway and the glutamate pathway of proline biosynthesis,and inhibition of proline degradation pathway.Furthermore,Cd~(2+) stress increased the production of H_2O_2,activities of the H_2O_2 producing -related enzymes(plasma membrane NADPH,cell wall polyamine oxidase,covalently and ionically-bound cell wall peroxidases),the product(MDA) of membrane lipid peroxidation and oxidation stress in the tobacco cells.Exogenous application of proline significantly decreased H_2O_2 production,MDA content and oxidation stress induced by Cd~(2+) stress.The inhibition of H_2O_2 production by exogenous proline might be due to the declined activities of the H_2O_2 producing-related enzymes under Cd~(2+) stress.
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Claims 12
Claim · model-written summary
Cd treatment significantly accumulated proline in tobacco suspension cells.
- Taxon
- tobacco
Nicotiana tabacume1 - Organ / stage
- suspension cellse1
- Treatment
- Cd~(2+) treatmente0
- Outcome
- accumulation of prolinee0
- Direction
- accumulatione0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd~(2+) treatment could lead to a significant accumulation of proline”
e1“tobacco(Nicotiana tabacum L.) suspension cells”
Claim · model-written summary
Cd sequentially up-regulated four proline biosynthesis enzymes.
- Taxon
- tobaccoNicotiana tabacume2
- Treatment
- Cd~(2+) treatmente1
- Outcome
- activities of the key enzymes(ornithine-8-aminotansferase,arginase,A'-pyrroline-5-carboxylate synthetase and glutamate dehydrogenase)e0
- Direction
- up-regulatione0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“sequential up-regulation of activities of the key enzymes(ornithine-8-aminotansferase,arginase,A'-pyrroline-5-carboxylate synthetase and glutamate dehydrogenase) for proline biosynthesis”
e1“Cd~(2+) treatment”
e2“tobacco(Nicotiana tabacum L.) suspension cells”
Claim · model-written summary
Cd inhibited proline dehydrogenase activity.
- Taxon
- tobaccoNicotiana tabacume2
- Treatment
- Cd~(2+) treatmente1
- Gene
- proline dehydrogenasee0
- Outcome
- activity of the key enzyme proline dehydrogenasee0
- Direction
- inhibitione0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“inhibition of activity of the key enzyme proline dehydrogenase for proline degradation”
e1“Cd~(2+) treatment”
e2“tobacco(Nicotiana tabacum L.) suspension cells”
Claim · model-written summary
The authors attributed Cd-induced proline accumulation to activated biosynthesis pathways and inhibited degradation.
- Taxon
- tobaccoNicotiana tabacume0
- Treatment
- Cd~(2+) stresse0
- Outcome
- proline accumulatione0
- Qualifier
- orderly activation of the ornithine pathway and the glutamate pathway of proline biosynthesis,and inhibition of proline degradation pathwaye0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd~(2+) stress-induced proline accumulation in the tobacco cells might be a combined result of the orderly activation of the ornithine pathway and the glutamate pathway of proline biosynthesis,and inhibition of proline degradation pathway”
Claim · model-written summary
Cd increased H_2O_2 production.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- Cd~(2+) stresse0
- Outcome
- production of H_2O_2e0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd~(2+) stress increased the production of H_2O_2”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
Claim · model-written summary
Cd increased activities of H_2O_2 producing enzymes.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- Cd~(2+) stresse0
- Outcome
- activities of the H_2O_2 producing -related enzymese0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd~(2+) stress increased the production of H_2O_2,activities of the H_2O_2 producing -related enzymes(plasma membrane NADPH,cell wall polyamine oxidase,covalently and ionically-bound cell wall peroxidases)”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
Claim · model-written summary
Cd increased MDA, the lipid peroxidation product.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- Cd~(2+) stresse0
- Outcome
- product(MDA) of membrane lipid peroxidatione0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cd~(2+) stress increased the production of H_2O_2,activities of the H_2O_2 producing -related enzymes(plasma membrane NADPH,cell wall polyamine oxidase,covalently and ionically-bound cell wall peroxidases),the product(MDA) of membrane lipid peroxidation”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
Claim · model-written summary
Cd increased oxidative stress.
- Taxon
- tobaccoNicotiana tabacume0
- Treatment
- Cd~(2+) stresse1
- Outcome
- oxidation stresse0
- Direction
- increasede1
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“and oxidation stress in the tobacco cells”
e1“Cd~(2+) stress increased the production of H_2O_2”
Claim · model-written summary
Exogenous proline significantly reduced Cd-induced H_2O_2 production.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- Exogenous application of prolinee0
- Outcome
- H_2O_2 productione0
- Direction
- decreasede0
- Comparator
- Cd~(2+) stresse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Exogenous application of proline significantly decreased H_2O_2 production,MDA content and oxidation stress induced by Cd~(2+) stress”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
Claim · model-written summary
Exogenous proline significantly reduced Cd-induced MDA content.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- Exogenous application of prolinee0
- Outcome
- MDA contente0
- Direction
- decreasede0
- Comparator
- Cd~(2+) stresse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Exogenous application of proline significantly decreased H_2O_2 production,MDA content and oxidation stress induced by Cd~(2+) stress”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
Claim · model-written summary
Exogenous proline significantly reduced Cd-induced oxidative stress.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- Exogenous application of prolinee0
- Outcome
- oxidation stresse0
- Direction
- decreasede0
- Comparator
- Cd~(2+) stresse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Exogenous application of proline significantly decreased H_2O_2 production,MDA content and oxidation stress induced by Cd~(2+) stress”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
Claim · model-written summary
The authors attributed proline suppression of H_2O_2 to lower activity of H_2O_2 producing enzymes.
- Taxon
- tobaccoNicotiana tabacume1
- Treatment
- exogenous prolinee0
- Outcome
- H_2O_2 productione0
- Qualifier
- declined activities of the H_2O_2 producing-related enzymese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The inhibition of H_2O_2 production by exogenous proline might be due to the declined activities of the H_2O_2 producing-related enzymes under Cd~(2+) stress”
e1“Tobacco(Nicotiana tabacum L.) Suspension Cells”
The same questions in other papers
cadmium atom · physiology: enzyme activity · Nicotiana tabacum (tobacco)Positive and negative results
1 in the opposite direction
- positive
proline · physiology: oxidative · Nicotiana tabacum (tobacco)Positive and negative results
2 papers in the same direction as this paper · 1 in the opposite direction
- no effect
- positive
- positive
cadmium atom · yield · Nicotiana tabacum (tobacco)Results agree
2 papers in the same direction as this paper
- negative
- no effect
cadmium atom · physiology: oxidative · Nicotiana tabacum (tobacco)Results agree
7 papers in the same direction as this paper
- negative
- negative
- negative
4 papers more in this group
See all 8 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.