Abstract
Systemic acquired resistance (SAR) is a broad-spectrum, systemic defense response that is activated in many plant species after pathogen infection. We have previously described Arabidopsis mutants that constitutively express SAR and concomitantly develop lesions simulating disease (lsd). Here, we describe two new mutants, lsd6 and lsd7, that develop spontaneous necrotic lesions and possess elevated levels of salicylic acid (SA) as well as heightened disease resistance, similar to the previously characterized lsd and accelerated cell death (acd2) mutants. Genetic analysis of lsd6 and lsd7 showed that the mutant phenotypes segregated as simple dominant traits. When crossed with transgenic Arabidopsis plants containing the SA-degrading enzyme salicylate hydroxylase, the F1 progeny showed suppression of both SAR gene expression and resistance. In addition, salicylate hydroxylase suppressed lesion formation in the F1 progeny, suggesting that SA or some SA-dependent process may have a role in pathogen-associated cell death. Surprisingly, lesions were restored in the lsd6 F1 progeny after the application of either 2,6-dichloroisonicotinic acid or SA. Lesions were not restored by treatment with either compound in the lsd7 F1 plants. Our findings demonstrate that steps early in the signal transduction pathway leading to SAR and disease resistance are potentiated by later events, suggesting feedback control of lesion formation.
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Claims 10
Claim · model-written summary
lsd6 and lsd7 develop spontaneous necrotic lesions.
- Taxon
- Arabidopsis
Arabidopsist0 - Material
- lsd6 and lsd7e0
- Outcome
- spontaneous necrotic lesionse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“two new mutants, lsd6 and lsd7, that develop spontaneous necrotic lesions”
t0“Arabidopsis”
Claim · model-written summary
lsd6 and lsd7 have elevated salicylic acid levels.
- Taxon
- ArabidopsisArabidopsist0
- Material
- lsd6 and lsd7e0
- Outcome
- elevated levels of salicylic acid (SA)e0
- Direction
- elevatede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“lsd6 and lsd7, that develop spontaneous necrotic lesions and possess elevated levels of salicylic acid (SA)”
t0“Arabidopsis”
Claim · model-written summary
lsd6 and lsd7 have heightened disease resistance.
- Taxon
- ArabidopsisArabidopsist0
- Material
- lsd6 and lsd7e1
- Outcome
- disease resistancee0
- Direction
- heightenede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“heightened disease resistance, similar to the previously characterized lsd and accelerated cell death (acd2) mutants”
e1“two new mutants, lsd6 and lsd7”
t0“Arabidopsis”
Claim · model-written summary
lsd6 and lsd7 phenotypes segregated as simple dominant traits.
- Taxon
- ArabidopsisArabidopsist0
- Material
- lsd6 and lsd7e0
- Outcome
- mutant phenotypes segregated as simple dominant traitse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Genetic analysis of lsd6 and lsd7 showed that the mutant phenotypes segregated as simple dominant traits.”
t0“Arabidopsis”
Claim · model-written summary
Salicylate hydroxylase suppressed SAR gene expression and resistance in F1 progeny.
- Taxon
- ArabidopsisArabidopsise0
- Treatment
- salicylate hydroxylasee0
- Gene
- salicylate hydroxylasee0
- Outcome
- SAR gene expression and resistancee0
- Direction
- suppressione0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“When crossed with transgenic Arabidopsis plants containing the SA-degrading enzyme salicylate hydroxylase, the F1 progeny showed suppression of both SAR gene expression and resistance.”
Claim · model-written summary
Salicylate hydroxylase suppressed lesion formation in F1 progeny.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- salicylate hydroxylasee0
- Outcome
- lesion formatione0
- Direction
- suppressede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“salicylate hydroxylase suppressed lesion formation in the F1 progeny”
t0“Arabidopsis”
Claim · model-written summary
2,6-dichloroisonicotinic acid restored lesions in lsd6 F1 progeny.
- Taxon
- ArabidopsisArabidopsist0
- Material
- lsd6e0
- Treatment
- 2,6-dichloroisonicotinic acide0
- Outcome
- lesionse0
- Direction
- restorede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“lesions were restored in the lsd6 F1 progeny after the application of either 2,6-dichloroisonicotinic acid or SA.”
t0“Arabidopsis”
Claim · model-written summary
SA restored lesions in lsd6 F1 progeny.
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“lesions were restored in the lsd6 F1 progeny after the application of either 2,6-dichloroisonicotinic acid or SA.”
t0“Arabidopsis”
Claim · model-written summary
Neither compound restored lesions in lsd7 F1 plants.
- Taxon
- ArabidopsisArabidopsist0
- Material
- lsd7e0
- Treatment
- either compounde0
- Outcome
- Lesionse0
- Direction
- not restorede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Lesions were not restored by treatment with either compound in the lsd7 F1 plants.”
t0“Arabidopsis”
Claim · model-written summary
The authors infer feedback control of lesion formation in SAR signaling.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- feedback control of lesion formatione0
- Qualifier
- signal transduction pathway leading to SAR and disease resistancee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“steps early in the signal transduction pathway leading to SAR and disease resistance are potentiated by later events, suggesting feedback control of lesion formation.”
t0“Arabidopsis”
The same questions in other papers
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See all 20 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.