Abstract
Bacterial effector proteins secreted through the type III secretion system (TTSS) play a crucial role in causing plant and human diseases. Although the ability of type III effectors to trigger defense responses in resistant plants is well understood, the disease-promoting functions of type III effectors in susceptible plants are largely enigmatic. Previous microscopic studies suggest that in susceptible plants the TTSS of plant-pathogenic bacteria transports suppressors of a cell wall-based plant defense activated by the TTSS-defective hrp mutant bacteria. However, the identity of such suppressors has remained elusive. We discovered that the Pseudomonas syringae TTSS down-regulated the expression of a set of Arabidopsis genes encoding putatively secreted cell wall and defense proteins in a salicylic acid-independent manner. Transgenic expression of AvrPto repressed a similar set of host genes, compromised defense-related callose deposition in the host cell wall, and permitted substantial multiplication of an hrp mutant. AvrPto is therefore one of the long postulated suppressors of an salicylic acid-independent, cell wall-based defense that is aimed at hrp mutant bacteria.
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Claims 5
Claim · model-written summary
Pseudomonas syringae TTSS down-regulated a set of Arabidopsis genes encoding secreted cell wall and defense proteins, independent of salicylic acid.
- Taxon
- Arabidopsis
Arabidopsist0 - Treatment
- Pseudomonas syringae TTSSe1
- Interactor
- Pseudomonas syringae
Pseudomonas syringaee1pathogen - Outcome
- expression of a set of Arabidopsis genes encoding putatively secreted cell wall and defense proteinse1
- Direction
- down-regulatede1
- Qualifier
- in a salicylic acid-independent mannere1
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants”
e1“We discovered that the Pseudomonas syringae TTSS down-regulated the expression of a set of Arabidopsis genes encoding putatively secreted cell wall and defense proteins in a salicylic acid-independent manner”
Claim · model-written summary
Transgenic AvrPto repressed a set of host genes similar to those down-regulated by the Pseudomonas syringae TTSS.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Transgenic expression of AvrPtoe2
- Gene
- AvrPtoe2
- Outcome
- host genese2
- Direction
- repressede2
- Qualifier
- a similar sete2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants”
e2“Transgenic expression of AvrPto repressed a similar set of host genes, compromised defense-related callose deposition in the host cell wall, and permitted substantial multiplication of an hrp mutant”
Claim · model-written summary
Transgenic AvrPto compromised defense-related callose deposition in the host cell wall.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Transgenic expression of AvrPtoe2
- Gene
- AvrPtoe2
- Outcome
- defense-related callose deposition in the host cell walle2
- Direction
- compromisede2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants”
e2“Transgenic expression of AvrPto repressed a similar set of host genes, compromised defense-related callose deposition in the host cell wall, and permitted substantial multiplication of an hrp mutant”
Claim · model-written summary
Transgenic AvrPto permitted substantial multiplication of an hrp mutant in Arabidopsis.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- Transgenic expression of AvrPtoe2
- Interactor
- hrp mutante2pathogen
- Gene
- AvrPtoe2
- Outcome
- multiplication of an hrp mutante2
- Direction
- permitted substantial multiplicatione2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants”
e2“Transgenic expression of AvrPto repressed a similar set of host genes, compromised defense-related callose deposition in the host cell wall, and permitted substantial multiplication of an hrp mutant”
Claim · model-written summary
AvrPto is proposed as one of the long-postulated suppressors of a salicylic acid-independent, cell wall-based defense.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- AvrPtoe3
- Outcome
- salicylic acid-independent, cell wall-based defensee3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants”
e3“AvrPto is therefore one of the long postulated suppressors of an salicylic acid-independent, cell wall-based defense that is aimed at hrp mutant bacteria”
The same questions in other papers
Pseudomonas syringae · molecular: expression · ArabidopsisPositive and negative results
3 papers in the same direction as this paper · 6 in the opposite direction
- no effect
- positive
- positive
6 papers more in this group
See all 10 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.