Abstract
Repeated and widespread use of single chemical pesticides raises concerns about efficiency and safety, developing multi-component synergistic pesticides provides a new route for efficient control of diseases. Most commercial compound formulations are open systems with non-adjustable released rates, resulting in a high frequency of applications. Meanwhile, although nano pesticide delivery systems constructed with different carrier materials have been extensively studied, realizing their actual scale-up production still has important practical significance due to the large-scale field application. In this study, a boscalid and pyraclostrobin dual-loaded nano pesticide system (BPDN) was constructed with industrial-grade carrier materials to facilitate the realization of large-scale production. The optimal industrial-scale preparation mechanism of BPDN was studied with surfactants as key factors. When agricultural emulsifier No.600 and polycarboxylate are used as the ratio of 1:2 in the preparation process, the BPDN has a spherical structure with an average size of 270 nm and exhibits superior physical stability. Compared with commercial formulation, BPDN maintains rate-stabilized release up to 5 times longer, exhibits better dispersion and spreading performance on foliar, has more than 20% higher deposition amounts, and reduces loss. A single application of BPDN could efficiently control tomato gray mold during the growing period of tomatoes due to extended duration and combinatory effectiveness, reducing two application times and labor costs. Toxicology tests on various objects systematically demonstrated that BPDN has improved safety for HepG2 cells, and nontarget organism earthworms. This research provides insight into creating safe, efficient, and environmentally friendly pesticide production to reduce manual operation times and labor costs. Accompanied by production strategies that can be easily scaled up industrially, this contributes to the efficient use of resources for sustainable agriculture.
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Claims 7
Claim · model-written summary
BPDN with a 1:2 emulsifier ratio was spherical, averaged 270 nm and had superior stability.
- Treatment
- agricultural emulsifier No.600 and polycarboxylatee0
- Outcome
- spherical structuree0
- Value
- 270 nme0
Not reportedTaxon
Verbatim
e0“When agricultural emulsifier No.600 and polycarboxylate are used as the ratio of 1:2 in the preparation process, the BPDN has a spherical structure with an average size of 270 nm and exhibits superior physical stability.”
Claim · model-written summary
BPDN release lasted up to five times longer than commercial formulation.
Not reportedTaxon
Verbatim
e0“Compared with commercial formulation, BPDN maintains rate-stabilized release up to 5 times longer”
Claim · model-written summary
BPDN improved dispersion and foliar spreading.
Not reportedTaxonComparatorValue
Verbatim
e0“exhibits better dispersion and spreading performance on foliar”
Claim · model-written summary
BPDN raised foliar deposition by more than 20%.
Not reportedTaxon
Verbatim
e0“has more than 20% higher deposition amounts, and reduces loss.”
Claim · model-written summary
BPDN reduced foliar loss.
Not reportedTaxonComparatorValue
Verbatim
e0“reduces loss.”
Claim · model-written summary
One BPDN application controlled tomato gray mold and reduced two application times.
- Taxon
- tomatoes
Solanum lycopersicume0 - Treatment
- single application of BPDNe0
- Outcome
- tomato gray molde0
- Direction
- controle0
- Value
- two application timese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A single application of BPDN could efficiently control tomato gray mold during the growing period of tomatoes due to extended duration and combinatory effectiveness, reducing two application times and labor costs.”
Claim · model-written summary
BPDN showed improved safety for HepG2 cells and earthworms.
- Outcome
- safety for HepG2 cells, and nontarget organism earthwormse0
Not reportedTaxon
Verbatim
e0“BPDN has improved safety for HepG2 cells, and nontarget organism earthworms.”
The same questions in other papers
insecticide · organism · Solanum lycopersicum (tomato)Positive and negative results
1 paper in the same direction as this paper · 1 in the opposite direction
- no effect
- positive
nanoparticle · organism · Solanum lycopersicum (tomato)Positive and negative results
4 papers in the same direction as this paper · 1 in the opposite direction
- negative
- positive
- positive
2 papers more in this group
See all 6 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.