Abstract
Pomegranate fruit has exposed various health benefits in many recent studies due to its rich content of bioactive chemical compounds. This study was carried out to investigate the content of these bioactive compounds in pomegranate fruit along with its antimicrobial and antitumor effects. Pomegranate peel powder and juice were analyzed for its phytochemical constituent content ( total phenols, total flavonoids). Phenols and flavonoids contents were estimated qualitative and quantitative using HPLC technique. Furthermore, antitumor activity was tested in vitro on human cell lines. Likewise, antimicrobial and antioxidant activity were investigated. The results showed that the both ethanolic and aqueous extracts of juice and peels powder have antitumor and antimicrobial activity.Phytochemicals have shown superior content in peels than juice including total polyphenols 61.63 and 15.93 mg/g, and total flavonoids 49.3 and 25.85 mg/g, in peels and juice, respectively. Peels extract has exhibited significant antimicrobial activity higher than aqueous extract of juice at 1000 ppm concentration. Thus, peels and juice extracts demonstrated higher antimicrobial activity against E.coli, fungi and yeast. In the test of pomegranate peels and juice extracts for the protective effect against human cell lines, the pomegranate extracts and AgNPs exhibited significant protective effect.In conclusion, our study suggested that pomegranate fruits or its extracts can use as antitumor and antimicrobial agents. Pomegranate fruits are sources of bioactive compounds such as phenolic and flavonoids with potentially high antioxidant activities.
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Claims 8
Claim · model-written summary
Total polyphenols were higher in peels than in juice (61.63 and 15.93 mg/g).
- Taxon
- Punica granatum
Punica granatumt0 - Organ / stage
- peelse0
- Outcome
- total polyphenolse0
- Direction
- superiore0
- Value
- 61.63 and 15.93 mg/ge0
- Comparator
- juicee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Pomegranate Fruit (Punica granatum L)”
e0“Phytochemicals have shown superior content in peels than juice including total polyphenols 61.63 and 15.93 mg/g, and total flavonoids 49.3 and 25.85 mg/g, in peels and juice, respectively”
Claim · model-written summary
Total flavonoids were higher in peels than in juice (49.3 and 25.85 mg/g).
- Taxon
- Punica granatumPunica granatumt0
- Organ / stage
- peelse0
- Outcome
- total flavonoidse0
- Direction
- superiore0
- Value
- 49.3 and 25.85 mg/ge0
- Comparator
- juicee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Pomegranate Fruit (Punica granatum L)”
e0“Phytochemicals have shown superior content in peels than juice including total polyphenols 61.63 and 15.93 mg/g, and total flavonoids 49.3 and 25.85 mg/g, in peels and juice, respectively”
Claim · model-written summary
Peel extract had significantly higher antimicrobial activity than the aqueous juice extract at 1000 ppm.
- Taxon
- Punica granatumPunica granatumt0
- Treatment
- Peels extracte1
- Outcome
- antimicrobial activitye1
- Direction
- highere1
- Qualifier
- 1000 ppm concentratione1
- Comparator
- aqueous extract of juicee1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Pomegranate Fruit (Punica granatum L)”
e1“Peels extract has exhibited significant antimicrobial activity higher than aqueous extract of juice at 1000 ppm concentration”
Claim · model-written summary
Peel and juice extracts showed higher antimicrobial activity against E. coli, fungi and yeast.
- Taxon
- Punica granatumPunica granatumt0
- Treatment
- peels and juice extractse2
- Interactor
- E.coli
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Escherichia colie2other - Second interactor
- yeaste2other
- Outcome
- antimicrobial activitye2
- Direction
- highere2
- Qualifier
- fungie2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
t0“Pomegranate Fruit (Punica granatum L)”
e2“Thus, peels and juice extracts demonstrated higher antimicrobial activity against E.coli, fungi and yeast”
Claim · model-written summary
Ethanolic and aqueous extracts of juice and peel powder had antitumour and antimicrobial activity.
- Taxon
- Punica granatumPunica granatumt0
- Treatment
- ethanolic and aqueous extracts of juice and peels powdere3
- Outcome
- antitumor and antimicrobial activitye3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Pomegranate Fruit (Punica granatum L)”
e3“The results showed that the both ethanolic and aqueous extracts of juice and peels powder have antitumor and antimicrobial activity”
Claim · model-written summary
Pomegranate extracts had a significant protective effect on human cell lines.
- Taxon
- Punica granatumPunica granatumt0
- Treatment
- pomegranate extractse4
- Outcome
- protective effecte4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Pomegranate Fruit (Punica granatum L)”
e4“the pomegranate extracts and AgNPs exhibited significant protective effect”
Claim · model-written summary
Pomegranate fruits are potentially rich in bioactive compounds with high antioxidant activities.
- Taxon
- Pomegranate fruitsPunica granatume5
- Outcome
- antioxidant activitiese5
- Qualifier
- potentially highe5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e5“Pomegranate fruits are sources of bioactive compounds such as phenolic and flavonoids with potentially high antioxidant activities”
Claim · model-written summary
Pomegranate fruits or their extracts can be used as antitumour and antimicrobial agents.
- Taxon
- pomegranate fruitsPunica granatume6
- Outcome
- use as antitumor and antimicrobial agentse6
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e6“pomegranate fruits or its extracts can use as antitumor and antimicrobial agents”
The same questions in other papers
botanical · disease · Punica granatum (pomegranate)Results agree
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- positive
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See all 13 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.