Abstract
The AVR9 peptide of the fungal pathogen Cladosporium fulvum and the INF1 protein of the oomycete pathogen Phytophthora infestans elicit the hypersensitive response (HR) on Cf9 tomato or Cf-9 transgenic tobacco and on all cultivars of tobacco, respectively. Expression of either the functional Avr9 or inf1 genes from engineered potato virus X (PVX) genomes resulted in localized HR lesions on tobacco plants responsive to the elicitors and inhibited spread of the recombinant virus. In contrast, PVX derivatives producing mutant forms of AVR9 and INF1 with reduced elicitor activity caused systemic necrotic and/or mosaic symptoms, and were unable to inhibit PVX spread. These results demonstrate that HR is a highly versatile defense mechanism active against unrelated pathogens irrespective of the HR-inducing agent, and that resistance to recombinant PVX in tobacco is correlated with the strength of the transgene-encoded elicitor.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 2
Claim · model-written summary
Functional Avr9 or inf1 in PVX induced localized hypersensitive lesions and limited virus spread in responsive tobacco.
- Taxon
- tobacco
Nicotiana tabacume0 - Treatment
- engineered potato virus X (PVX) genomese0
- Interactor
- potato virus XPotato virus Xe0pathogen
- Gene
- Avr9 or inf1e0
- Outcome
- localized HR lesionse0
- Direction
- resulted ine0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Expression of either the functional Avr9 or inf1 genes from engineered potato virus X (PVX) genomes resulted in localized HR lesions on tobacco plants responsive to the elicitors and inhibited spread of the recombinant virus.”
Claim · model-written summary
Mutant AVR9 or INF1 PVX caused systemic disease symptoms and failed to inhibit viral spread.
- Taxon
- TobaccoNicotiana tabacumt0
- Treatment
- PVX derivatives producing mutant forms of AVR9 and INF1e0
- Interactor
- PVXPotato virus Xe0pathogen
- Gene
- AVR9 and INF1e0
- Outcome
- systemic necrotic and/or mosaic symptomse0
- Direction
- causede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“PVX derivatives producing mutant forms of AVR9 and INF1 with reduced elicitor activity caused systemic necrotic and/or mosaic symptoms, and were unable to inhibit PVX spread.”
t0“on Tobacco”
The same questions in other papers
Solanum tuberosum · Potato virus X · Nicotiana tabacum (tobacco)Positive and negative results
2 papers in the same direction as this paper · 10 in the opposite direction
- negative
- no effect
- negative
9 papers more in this group
See all 13 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.