Abstract
Because micronutrients in human diets ultimately come from plant sources, malnutrition of essential minerals is a significant public health concern. By increasing the expression of nicotianamine synthase (NAS), we fortified the level of bioavailable iron in rice seeds. Activation of iron deficiency-inducible OsNAS2 resulted in a rise in Fe content (3.0-fold) in mature seeds. Its ectopic expression also increased that content. Enhanced expression led to higher tolerance of Fe deficiency and better growth under elevated pH. Mice fed with OsNAS2-D1 seeds recovered more rapidly from anemia, indicating that bioavailable Fe contents were improved by this increase in OsNAS2 expression.
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Claims 5
Claim · model-written summary
OsNAS2 activation raised Fe content in mature rice seeds 3.0-fold.
- Taxon
- Rice
Oryza sativat0 - Organ / stage
- mature seedse0
- Treatment
- Activation of iron deficiency-inducible OsNAS2e0
- Gene
- OsNAS2e0
- Outcome
- Fe contente0
- Direction
- risee0
- Value
- 3.0-folde0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Activation of iron deficiency-inducible OsNAS2 resulted in a rise in Fe content (3.0-fold) in mature seeds”
t0“Rice”
Claim · model-written summary
Ectopic OsNAS2 expression increased seed Fe content.
- Taxon
- RiceOryza sativat0
- Treatment
- ectopic expressione0
- Gene
- OsNAS2e1
- Outcome
- Fe contente2
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Its ectopic expression also increased that content”
e1“iron deficiency-inducible OsNAS2”
e2“a rise in Fe content (3.0-fold)”
t0“Rice”
Claim · model-written summary
Enhanced OsNAS2 expression increased tolerance of Fe deficiency.
- Taxon
- RiceOryza sativat0
- Treatment
- Enhanced expressione0
- Gene
- OsNAS2e1
- Outcome
- tolerance of Fe deficiencye0
- Direction
- highere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Enhanced expression led to higher tolerance of Fe deficiency”
e1“iron deficiency-inducible OsNAS2”
t0“Rice”
Claim · model-written summary
Enhanced OsNAS2 expression improved growth under elevated pH.
- Taxon
- RiceOryza sativat0
- Treatment
- Enhanced expressione0
- Gene
- OsNAS2e1
- Outcome
- growthe0
- Direction
- bettere0
- Qualifier
- elevated pHe0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Enhanced expression led to higher tolerance of Fe deficiency and better growth under elevated pH”
e1“iron deficiency-inducible OsNAS2”
t0“Rice”
Claim · model-written summary
Mice fed OsNAS2-D1 seeds recovered more rapidly from anemia.
- Taxon
- RiceOryza sativat0
- Material
- OsNAS2-D1e0
- Outcome
- recovered more rapidly from anemiae0
- Direction
- more rapidlye0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Mice fed with OsNAS2-D1 seeds recovered more rapidly from anemia”
t0“Rice”
The same questions in other papers
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overexpression · nutrient: content · Oryza sativa (rice)Positive and negative results
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- no effect
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See all 6 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.