Paper · 1968 · Science

Vernolepin: A New, Reversible Plant Growth Inhibitor

Luis Sequeira; Richard J. Hemingway; S. Morris Kupchan

6
claims
9
verbatim quotes
36
citations
1
research areas
—
Not open access

Abstract

Vernolepin (5 to 50 micrograms per milliliter), a novel sesquiterpenoid dilactone obtained from Vernonia hymenolepis, inhibits extension growth (from 20 to 80 percent) of wheat coleoptile sections. Inhibited tissues appear normal and their respiration is unaffected. If the inhibited sections are washed and subsequently treated with indole-3-acetic acid, the tissues respond to the auxin, but the degree of elongation is determined by the length of prior treatment with vernolepin. Administered simultaneously, increasing concentrations of auxin will significantly reduce the inhibitory effect of vernolepin, but there is no evidence for a competitive interaction between the two substances.

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The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.

Claims 6

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Vernolepin inhibited wheat coleoptile extension by 20 to 80 percent.

Organ / stage
coleoptile sectionse0
Treatment
Vernolepin (5 to 50 micrograms per milliliter)e0
Outcome
extension growthe0
Direction
inhibitse0
Value
20 to 80 percente0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Vernolepin (5 to 50 micrograms per milliliter), a novel sesquiterpenoid dilactone obtained from Vernonia hymenolepis, inhibits extension growth (from 20 to 80 percent) of wheat coleoptile sections.”

✓ located verbatim in the source · abstract, characters 0–197 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Vernolepin-inhibited wheat tissues appeared normal.

Outcome
Inhibited tissues appear normale0

Not reportedTaxon

Verbatim

t0

“Plant Growth Inhibitor”

✓ located verbatim in the source · title, characters 30–52 · show in text ↑
e0

“Inhibited tissues appear normal”

✓ located verbatim in the source · abstract, characters 198–229 · show in text ↑
Intervention effectobservedoriginal resultno effectmeasured

Claim · model-written summary

Respiration of vernolepin-inhibited wheat tissues was unaffected.

Treatment
Vernolepin (5 to 50 micrograms per milliliter)e0
Outcome
respiratione1
Direction
unaffectede1

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Vernolepin (5 to 50 micrograms per milliliter), a novel sesquiterpenoid dilactone obtained from Vernonia hymenolepis, inhibits extension growth (from 20 to 80 percent) of wheat coleoptile sections.”

✓ located verbatim in the source · abstract, characters 0–197 · show in text ↑
e1

“their respiration is unaffected”

✓ located verbatim in the source · abstract, characters 234–265 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

After washing and auxin treatment, inhibited wheat sections responded, with elongation depending on prior vernolepin duration.

Treatment
indole-3-acetic acide0
Outcome
respond to the auxine0
Qualifier
length of prior treatment with vernolepine0

Not reportedTaxonComparatorDirection

Verbatim

e0

“If the inhibited sections are washed and subsequently treated with indole-3-acetic acid, the tissues respond to the auxin, but the degree of elongation is determined by the length of prior treatment with vernolepin.”

✓ located verbatim in the source · abstract, characters 267–482 · show in text ↑
t0

“Plant Growth Inhibitor”

✓ located verbatim in the source · title, characters 30–52 · show in text ↑
Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Increasing simultaneous auxin concentrations significantly reduced vernolepin inhibition.

Treatment
increasing concentrations of auxine0
Outcome
inhibitory effect of vernolepine0
Direction
reducee0

Not reportedTaxonComparator

Verbatim

e0

“Administered simultaneously, increasing concentrations of auxin will significantly reduce the inhibitory effect of vernolepin”

✓ located verbatim in the source · abstract, characters 483–608 · show in text ↑
Observationobservedoriginal resultno effectmeasured

Claim · model-written summary

There was no evidence of competitive interaction between auxin and vernolepin.

Outcome
no evidence for a competitive interactione0

Not reportedTaxon

Verbatim

e0

“there is no evidence for a competitive interaction between the two substances”

✓ located verbatim in the source · abstract, characters 614–691 · show in text ↑

indole-3-acetic acid · physiology: hormones · Triticum aestivum (wheat)Positive and negative results

4 papers: 3 positive, 1 negative or no effect

2 papers in the same direction as this paper · 1 in the opposite direction

  1. no effect
  2. positive
  3. positive
See all 4 papers →

class · molecular: metabolites · Triticum aestivum (wheat)Positive and negative results

18 papers: 15 positive, 3 negative or no effect

14 papers in the same direction as this paper · 3 in the opposite direction

  1. negative
  2. negative
  3. negative

14 papers more in this group

See all 18 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.