Abstract
Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley. Deoxynivalenol (DON) produced by the pathogen is an important mycotoxins and virulence factor. Because oxidative burst is a common defense response and reactive oxygen species (ROS) induces DON production, in this study, we characterized functional relationships of three stress-related transcription factor genes FgAP1, FgATF1 and FgSKN7. Although all of them played a role in tolerance to oxidative stress, deletion of FgAP1 or FgATF1 had no significant effect on DON production. In contrast, Fgskn7 mutants were reduced in DON production and defective in H2 O2 -induced TRI gene expression. The Fgap1 mutant had no detectable phenotype other than increased sensitivity to H2 O2 and Fgap1 Fgatf1 and Fgap1 Fgskn7 mutants lacked additional or more severe phenotypes than the single mutants. The Fgatf1, but not Fgskn7, mutant was significantly reduced in virulence and delayed in ascospore release. The Fgskn7 Fgatf1 double mutant had more severe defects in growth, conidiation and virulence than the Fgatf1 or Fgskn7 mutant. Instead of producing four-celled ascospores, it formed eight small, single-celled ascospores in each ascus. Therefore, FgSKN7 and FgATF1 must have overlapping functions in intracellular ROS signalling for growth, development and pathogenesis in F. graminearum.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 11
Claim · model-written summary
FgAP1, FgATF1 and FgSKN7 each played a role in tolerance to oxidative stress.
- Taxon
- wheat and barley
.jpg?width=60)
Hordeum vulgare
Triticum aestivume0 - Treatment
- deletion of FgAP1 or FgATF1e5
- Outcome
- tolerance to oxidative stresse5
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e5“Although all of them played a role in tolerance to oxidative stress, deletion of FgAP1 or FgATF1 had no significant effect on DON production”
Claim · model-written summary
Deletion of FgAP1 or FgATF1 had no significant effect on DON production by Fusarium graminearum.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- deletion of FgAP1 or FgATF1e5
- Interactor
- Fusarium graminearum
_on_Corn_(Zea_mays)_at_Waimea%2C_Hawaii.jpg?width=60)
Fusarium graminearume0pathogen - Outcome
- DON productione5
- Direction
- no significant effecte5
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_on_Corn_(Zea_mays)_at_Waimea%2C_Hawaii.jpg?width=500)
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e5“Although all of them played a role in tolerance to oxidative stress, deletion of FgAP1 or FgATF1 had no significant effect on DON production”
Claim · model-written summary
Fgskn7 mutants reduced DON production by Fusarium graminearum.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgskn7 mutantse1
- Interactor
- Fusarium graminearumFusarium graminearume0pathogen
- Outcome
- DON productione1
- Direction
- reducede1
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e1“Fgskn7 mutants were reduced in DON production and defective in H2 O2 -induced TRI gene expression”
Claim · model-written summary
Fgskn7 mutants were defective in H2O2-induced TRI gene expression.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgskn7 mutantse1
- Interactor
- Fusarium graminearumFusarium graminearume0pathogen
- Gene
- TRIe1
- Outcome
- TRI gene expressione1
- Direction
- defectivee1
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e1“Fgskn7 mutants were reduced in DON production and defective in H2 O2 -induced TRI gene expression”
Claim · model-written summary
The Fgap1 mutant had no detectable phenotype except increased sensitivity to H2O2.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgap1 mutante2
- Outcome
- sensitivity to H2 O2e2
- Direction
- increasede2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e2“The Fgap1 mutant had no detectable phenotype other than increased sensitivity to H2 O2 and Fgap1 Fgatf1 and Fgap1 Fgskn7 mutants lacked additional or more severe phenotypes than the single mutants”
Claim · model-written summary
Fgap1 Fgatf1 and Fgap1 Fgskn7 double mutants lacked additional or more severe phenotypes than the single mutants.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgap1 Fgatf1 and Fgap1 Fgskn7 mutantse2
- Outcome
- phenotypese2
- Direction
- lacked additional or more severee2
- Comparator
- single mutantse2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e2“The Fgap1 mutant had no detectable phenotype other than increased sensitivity to H2 O2 and Fgap1 Fgatf1 and Fgap1 Fgskn7 mutants lacked additional or more severe phenotypes than the single mutants”
Claim · model-written summary
Fgatf1 mutant was significantly reduced in virulence on wheat and barley.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgatf1, but not Fgskn7, mutante3
- Interactor
- Fusarium graminearumFusarium graminearume0pathogen
- Outcome
- virulencee3
- Direction
- significantly reducede3
- Comparator
- Fgskn7e3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e3“The Fgatf1, but not Fgskn7, mutant was significantly reduced in virulence and delayed in ascospore release”
Claim · model-written summary
Fgatf1 mutant delayed ascospore release.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgatf1, but not Fgskn7, mutante3
- Outcome
- ascospore releasee3
- Direction
- delayede3
- Comparator
- Fgskn7e3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e3“The Fgatf1, but not Fgskn7, mutant was significantly reduced in virulence and delayed in ascospore release”
Claim · model-written summary
Fgskn7 Fgatf1 double mutant had more severe defects in growth, conidiation and virulence than the single mutants.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Treatment
- Fgskn7 Fgatf1 double mutante4
- Outcome
- growth, conidiation and virulencee4
- Direction
- more severe defectse4
- Comparator
- Fgatf1 or Fgskn7 mutante4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e4“The Fgskn7 Fgatf1 double mutant had more severe defects in growth, conidiation and virulence than the Fgatf1 or Fgskn7 mutant. Instead of producing four-celled ascospores, it formed eight small, single-celled ascospores in each ascus”
Claim · model-written summary
Fgskn7 Fgatf1 double mutant formed eight small, single-celled ascospores in each ascus instead of four-celled ascospores.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Interactor
- Fusarium graminearumFusarium graminearume0pathogen
- Outcome
- ascosporese4
- Qualifier
- eight small, single-celled ascospores in each ascuse4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e4“The Fgskn7 Fgatf1 double mutant had more severe defects in growth, conidiation and virulence than the Fgatf1 or Fgskn7 mutant. Instead of producing four-celled ascospores, it formed eight small, single-celled ascospores in each ascus”
Claim · model-written summary
FgSKN7 and FgATF1 have overlapping functions in intracellular ROS signalling for growth, development and pathogenesis.
- Taxon
- wheat and barleyHordeum vulgareTriticum aestivume0
- Gene
- FgSKN7 and FgATF1e6
- Outcome
- overlapping functions in intracellular ROS signallinge6
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Fusarium head blight caused by Fusarium graminearum is one of the most destructive diseases of wheat and barley”
e6“FgSKN7 and FgATF1 must have overlapping functions in intracellular ROS signalling for growth, development and pathogenesis in F. graminearum”
The same questions in other papers
loss of function · Fusarium graminearum · Hordeum vulgare (barley)Positive and negative results
4 papers in the same direction as this paper · 3 in the opposite direction
- positive
- positive
- positive
4 papers more in this group
See all 8 papers →loss of function · Fusarium graminearum · Triticum aestivum (wheat)Positive and negative results
20 papers in the same direction as this paper · 40 in the opposite direction
- positive
- positive
- positive
57 papers more in this group
See all 61 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.