Claim · model-written summary
Recessive PMR4 mutations in Arabidopsis conferred strong resistance to multiple Plasmodiophora brassicae pathotypes.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae3 - Treatment
- Recessive PMR4 mutationse3
- Interactor
- P. brassicae
Plasmodiophora brassicaee3pathogen - Gene
- PMR4e3
- Outcome
- resistancee3
Not reportedComparatorDirection
Verbatim
e3“Recessive PMR4 mutations in Arabidopsis thaliana conferred strong resistance to multiple P. brassicae pathotypes, independent of salicylic acid-mediated plant immunity”
Title
Runbang Luo; Lipu Wang; Rui Wen; et al. The Plant Cell 2026. doi:10.1093/plcell/koag160
Other claims from this paper (9)
- Intervention effect Homozygous CRISPR-edited PMR4 orthologs in Brassica napus conferred resistance to powdery mildew and clubroot.
- Intervention effect Plasmodiophora brassicae infection induced callose deposition in Arabidopsis roots in a PMR4-dependent manner.
- Intervention effect Plasmodiophora brassicae infection induced callose deposition in Brassica napus roots in a PMR4-dependent manner.
- Intervention effect The pmr4-1 mutation did not affect primary infection by Plasmodiophora brassicae in Arabidopsis.
- Intervention effect The pmr4-1 mutation blocked pathogen entry from epidermal cells to the stele in a jasmonic acid signaling-dependent manner in Arabidopsis.
- Association Blocked pathogen entry in pmr4-1 coincided with accumulation of lignin-like and suberin compounds in periderm cell walls of Arabidopsis.
- Mechanism PMR4-encoded callose synthase is a host susceptibility factor facilitating secondary infection by Plasmodiophora brassicae.
- Recommendation PMR4 is a gene-editing target for enhancing resistance to powdery mildew and clubroot in Brassicaceae crops.
- Observation PMR4 was identified as a potential host susceptibility factor in Arabidopsis and Brassica napus.