Paper · 2023 · Studies on Ethno-Medicine

A Meta-analysis of the Efficacy of Homoeopathic Ultra High Dilutions on Wheat Plant Growth and Disease Management

Parth Aphale

6
claims
6
verbatim quotes
0
citations
2
research areas
✓
Open access

Abstract

Homeopathic medicines have been examined in plant models for various purposes like promotion of seed germination, growth and physiology of plants, plant disease control, secondary metabolites enhancement, metal detoxification, etc. However, a limited number of the studies question the reliability of the data, which restricts the use of homoeopathy in the plant system. Therefore this meta-analysis was undertaken to investigate the effect of various homoeopathic medicines on seed germination, growth and disease control in wheat (Triticumaestivum L.). A web search was performed on the National Library of Medicine’s PubMed search engine and 16 studies were retrieved based on inclusion and exclusion criterions. Using data from each study, two by two tables were prepared and fixed mean differences for plant growth, odd ratios for seed germination and risk ratio for disease control along with their ninety-five percent confidence intervals were calculated by Inverse Variance method using Review Manager 5.4.1 (Rev Man 5.4.1) software. Data suggests that gibberellic acid significantly reduces the wheat seedling/stalk growth in autumn season with mean difference of -3.99 (95% CI: -4.41, -3.51), with inconsistent effect in winter and spring season. Further, Arsenicum album treatment promoted the seedling growth in wheat with mean difference: 11.86 (95% CI: 11.67, 12.06), while there was no significant effect on seed germination, and odd ratio: 1.27 (95% CI: 0.87, 1.85, P = 0.22). Moreover, various homoeopathic agents significantly reduced the risk of Fusarium and Alternaria infection in wheat seeds. To conclude, meta-analysis of included studies suggests significant effects of homoeopathic agents in various aspects of wheat plant growth and disease management.

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Claims 6

Intervention effectobservedoriginal resultnegativesignificant (as stated)measured

Claim · model-written summary

Gibberellic acid reduced wheat seedling and stalk growth in autumn.

Treatment
gibberellic acide0
Outcome
wheat seedling/stalk growthe0
Direction
reducese0
Value
-3.99e0
Qualifier
autumn seasone0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Data suggests that gibberellic acid significantly reduces the wheat seedling/stalk growth in autumn season with mean difference of -3.99 (95% CI: -4.41, -3.51), with inconsistent effect in winter and spring season.”

✓ located verbatim in the source · abstract, characters 1042–1256 · show in text ↑
Observationobservedoriginal resultmixedmeasured

Claim · model-written summary

Gibberellic acid had inconsistent effects on growth in winter and spring.

Treatment
gibberellic acide0
Outcome
effect in winter and spring seasone0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Data suggests that gibberellic acid significantly reduces the wheat seedling/stalk growth in autumn season with mean difference of -3.99 (95% CI: -4.41, -3.51), with inconsistent effect in winter and spring season.”

✓ located verbatim in the source · abstract, characters 1042–1256 · show in text ↑
Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Arsenicum album promoted wheat seedling growth.

Treatment
Arsenicum album treatmente0
Outcome
seedling growthe0
Direction
promotede0
Value
11.86e0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Further, Arsenicum album treatment promoted the seedling growth in wheat with mean difference: 11.86 (95% CI: 11.67, 12.06), while there was no significant effect on seed germination, and odd ratio: 1.27 (95% CI: 0.87, 1.85, P = 0.22).”

✓ located verbatim in the source · abstract, characters 1257–1492 · show in text ↑
Intervention effectobservedoriginal resultno effectnot significant (as stated)measured

Claim · model-written summary

Arsenicum album showed no significant effect on wheat seed germination.

Treatment
Arsenicum album treatmente0
Outcome
seed germinatione0
Direction
no significant effecte0
Value
1.27e0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Further, Arsenicum album treatment promoted the seedling growth in wheat with mean difference: 11.86 (95% CI: 11.67, 12.06), while there was no significant effect on seed germination, and odd ratio: 1.27 (95% CI: 0.87, 1.85, P = 0.22).”

✓ located verbatim in the source · abstract, characters 1257–1492 · show in text ↑
Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Homeopathic agents significantly reduced Fusarium infection risk in wheat seeds.

Organ / stage
seedse0
Treatment
various homoeopathic agentse0
Interactor
FusariumFusariume0pathogen
Outcome
risk of Fusarium and Alternaria infectione0
Direction
reducede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗
Fusarium
Fusarium · Interactor · picture of the genus (one of its species)Public domain · Wikimedia Commons ↗

Verbatim

e0

“Moreover, various homoeopathic agents significantly reduced the risk of Fusarium and Alternaria infection in wheat seeds.”

✓ located verbatim in the source · abstract, characters 1493–1614 · show in text ↑
Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Homeopathic agents significantly reduced Alternaria infection risk in wheat seeds.

Organ / stage
seedse0
Treatment
various homoeopathic agentse0
Interactor
AlternariaAlternariae0pathogen
Outcome
risk of Fusarium and Alternaria infectione0
Direction
reducede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗
Alternaria
Alternaria · Interactor · picture of the genus (one of its species)http://phil.cdc.gov/phil_images/20030612/9/PHIL_3963_lores.jpg · Public domain · Wikimedia Commons ↗

Verbatim

e0

“Moreover, various homoeopathic agents significantly reduced the risk of Fusarium and Alternaria infection in wheat seeds.”

✓ located verbatim in the source · abstract, characters 1493–1614 · show in text ↑

arsenic atom · growth · Triticum aestivum (wheat)Results differ

15 papers: 3 positive, 12 negative or no effect

2 papers in the same direction as this paper · 12 in the opposite direction

  1. positive
  2. negative
  3. negative

11 papers more in this group

See all 15 papers →

Gibberellic acid · growth · Triticum aestivum (wheat)Results differ

67 papers: 54 positive, 13 negative or no effect

12 papers in the same direction as this paper · 54 in the opposite direction

  1. no effect
  2. positive
  3. positive

63 papers more in this group

See all 67 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.