Abstract
Scadoxus multiflorus is a traditionally used medicinal plant, widespread in Sub-Saharan Africa from Senegal to South Africa and in some places of Saudi Arabia and India. The present study aimed to analyze antimitotic and cytotoxic effects of leaf aqueous extract of S. multiflorus (LAESM) in Allium cepa root apical meristem cells. The root growth retardation, mitotic index (MI), cytological and mitotic abnormalities were analyzed in A. cepa root apical meristem cells after LAESM treatment. The LAESM induced a concentration-dependent A. cepa root growth retardation, MI decreased to a large extent in the treated samples. The LAESM induced mitotic, nuclear, and chromosomal abnormalities in A. cepa root tip cells. Thus, the present work indicates for the first time antimitotic and cytotoxic potentials of leaf aqueous extract of S. multiflorus.
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Claims 3
Claim · model-written summary
Scadoxus leaf extract caused concentration-dependent Allium root growth retardation.
- Taxon
- A. cepa
Allium cepae0 - Treatment
- LAESMe0
- Outcome
- root growth retardatione0
- Direction
- retardatione0
- Qualifier
- concentration-dependente0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The LAESM induced a concentration-dependent A. cepa root growth retardation”
Claim · model-written summary
Scadoxus leaf extract greatly decreased mitotic index in treated Allium samples.
- Taxon
- A. cepaAllium cepae1
- Treatment
- leaf aqueous extract of Scadoxus multiflorust0
- Outcome
- MIe0
- Direction
- decreasede0
- Qualifier
- to a large extente0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“MI decreased to a large extent in the treated samples”
t0“Leaf Aqueous Extract of Scadoxus multiflorus (Martyn) Raf. in Allium cepa Root Apical Meristem Cells”
e1“The LAESM induced a concentration-dependent A. cepa root growth retardation”
Claim · model-written summary
Scadoxus leaf extract induced mitotic, nuclear, and chromosomal abnormalities in Allium root tip cells.
- Taxon
- A. cepaAllium cepae0
- Organ / stage
- root tip cellse0
- Treatment
- LAESMe0
- Outcome
- mitotic, nuclear, and chromosomal abnormalitiese0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The LAESM induced mitotic, nuclear, and chromosomal abnormalities in A. cepa root tip cells”
The same questions in other papers
botanical · cytology · Allium cepa (onion)Positive and negative results
89 papers in the same direction as this paper · 26 in the opposite direction
- positive
- negative
- positive
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