Abstract
Our previous study has indicated that a long noncoding RNA (lncRNA), lncRNA39026, can be responsive to Phytophthora infestans infection. However, the function and regulation mechanism of lncRNA39026 during tomato resistance to P. infestans are unknown. In this study, an lncRNA39026 sequence was cloned from tomato Zaofen No. 2, and this sequence contained an endogenous target mimicry for miR168a, which might suppress the expression of miR168a. LncRNA39026 was strongly downregulated at 3 h in the tomato plants infected with P. infestans, and its expression level displayed a negative correlation with the expression level of miR168a and a positive correlation with the expression levels of SlAGO1 genes (target gene of miR168a) upon P. infestans infection. Tomato plants in which lncRNA39026 was overexpressed displayed enhanced resistance to P. infestans, decreased level of miR168a, and increased level of SlAGO1, whereas the resistance was impaired, level of miR168a was increased, and level of SlAGO1 was decreased after lncRNA39026 silencing. In addition, lncRNA39026 could also induce the expression of pathogenesis-related (PR) genes, as shown by increased and decreased expression levels of PR genes in tomato plants with overexpressed and silenced lncRNA39026, respectively. The result demonstrated that lncRNA39026 might function to decoy miR168a and affect the expression of PR genes in tomato plants, increasing resistance to disease.
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Claims 13
Claim · model-written summary
Tomato lncRNA39026 contains an endogenous target mimicry for miR168a.
- Taxon
- tomato
Solanum lycopersicume0 - Material
- Zaofen No. 2e0
- Gene
- lncRNA39026e0
- Outcome
- endogenous target mimicry for miR168ae0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“an lncRNA39026 sequence was cloned from tomato Zaofen No. 2, and this sequence contained an endogenous target mimicry for miR168a”
Claim · model-written summary
P. infestans infection strongly downregulated tomato lncRNA39026 at 3 h.
- Taxon
- tomatoSolanum lycopersicume0
- Treatment
- infected with P. infestanse0
- Interactor
- P. infestans
Phytophthora infestanse0pathogen - Gene
- LncRNA39026e0
- Outcome
- LncRNA39026e0
- Direction
- downregulatede0
- Value
- 3 he0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“LncRNA39026 was strongly downregulated at 3 h in the tomato plants infected with P. infestans”
Claim · model-written summary
During P. infestans infection, tomato lncRNA39026 expression correlated negatively with miR168a expression.
- Taxon
- tomatoSolanum lycopersicumt0
- Interactor
- P. infestansPhytophthora infestanse0pathogen
- Gene
- miR168ae0
- Outcome
- expression level of miR168ae0
- Direction
- negative correlatione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“its expression level displayed a negative correlation with the expression level of miR168a and a positive correlation with the expression levels of SlAGO1 genes (target gene of miR168a) upon P. infestans infection.”
t0“Tomato”
Claim · model-written summary
During P. infestans infection, tomato lncRNA39026 expression correlated positively with SlAGO1 expression.
- Taxon
- tomatoSolanum lycopersicumt0
- Interactor
- P. infestansPhytophthora infestanse0pathogen
- Gene
- SlAGO1 genese0
- Outcome
- expression levels of SlAGO1 genese0
- Direction
- positive correlatione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“its expression level displayed a negative correlation with the expression level of miR168a and a positive correlation with the expression levels of SlAGO1 genes (target gene of miR168a) upon P. infestans infection.”
t0“Tomato”
Claim · model-written summary
Overexpressing lncRNA39026 enhanced tomato resistance to P. infestans.
- Taxon
- TomatoSolanum lycopersicume0
- Treatment
- lncRNA39026 was overexpressede0
- Interactor
- P. infestansPhytophthora infestanse0pathogen
- Outcome
- resistance to P. infestanse0
- Direction
- enhancede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tomato plants in which lncRNA39026 was overexpressed displayed enhanced resistance to P. infestans, decreased level of miR168a, and increased level of SlAGO1”
Claim · model-written summary
Overexpressing lncRNA39026 decreased tomato miR168a level.
- Taxon
- TomatoSolanum lycopersicume0
- Treatment
- lncRNA39026 was overexpressede0
- Outcome
- level of miR168ae0
- Direction
- decreasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tomato plants in which lncRNA39026 was overexpressed displayed enhanced resistance to P. infestans, decreased level of miR168a, and increased level of SlAGO1”
Claim · model-written summary
Overexpressing lncRNA39026 increased tomato SlAGO1 level.
- Taxon
- TomatoSolanum lycopersicume0
- Treatment
- lncRNA39026 was overexpressede0
- Outcome
- level of SlAGO1e0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tomato plants in which lncRNA39026 was overexpressed displayed enhanced resistance to P. infestans, decreased level of miR168a, and increased level of SlAGO1”
Claim · model-written summary
Silencing lncRNA39026 impaired tomato resistance.
- Taxon
- TomatoSolanum lycopersicumt0
- Treatment
- lncRNA39026 silencinge0
- Outcome
- resistancee0
- Direction
- impairede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the resistance was impaired, level of miR168a was increased, and level of SlAGO1 was decreased after lncRNA39026 silencing.”
t0“Tomato”
Claim · model-written summary
Silencing lncRNA39026 increased tomato miR168a level.
- Taxon
- TomatoSolanum lycopersicumt0
- Treatment
- lncRNA39026 silencinge0
- Outcome
- level of miR168ae0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the resistance was impaired, level of miR168a was increased, and level of SlAGO1 was decreased after lncRNA39026 silencing.”
t0“Tomato”
Claim · model-written summary
Silencing lncRNA39026 decreased tomato SlAGO1 level.
- Taxon
- TomatoSolanum lycopersicumt0
- Treatment
- lncRNA39026 silencinge0
- Outcome
- level of SlAGO1e0
- Direction
- decreasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the resistance was impaired, level of miR168a was increased, and level of SlAGO1 was decreased after lncRNA39026 silencing.”
t0“Tomato”
Claim · model-written summary
Overexpressing lncRNA39026 increased tomato PR gene expression.
- Taxon
- tomatoSolanum lycopersicume0
- Treatment
- overexpressede0
- Outcome
- expression levels of PR genese0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“increased and decreased expression levels of PR genes in tomato plants with overexpressed and silenced lncRNA39026, respectively.”
Claim · model-written summary
Silencing lncRNA39026 decreased tomato PR gene expression.
- Taxon
- tomatoSolanum lycopersicume0
- Treatment
- silenced lncRNA39026e0
- Outcome
- expression levels of PR genese0
- Direction
- decreasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“increased and decreased expression levels of PR genes in tomato plants with overexpressed and silenced lncRNA39026, respectively.”
Claim · model-written summary
The authors suggest lncRNA39026 decoys miR168a and affects PR gene expression to increase tomato disease resistance.
- Taxon
- tomatoSolanum lycopersicume0
- Gene
- lncRNA39026e0
- Outcome
- resistance to diseasee0
- Direction
- increasinge0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“lncRNA39026 might function to decoy miR168a and affect the expression of PR genes in tomato plants, increasing resistance to disease.”
The same questions in other papers
loss of function · disease · Solanum lycopersicum (tomato)Positive and negative results
91 papers in the same direction as this paper · 63 in the opposite direction
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