Abstract
The plant hormone jasmonic acid (JA) plays a key role in the environmental stress responses and developmental processes of plants. Although ATMYC2/JASMONATE-INSENSITIVE1 (JIN1) is a major positive regulator of JA-inducible gene expression and essential for JA-dependent developmental processes in Arabidopsis thaliana, molecular mechanisms underlying the control of ATMYC2/JIN1 expression remain largely unknown. Here, we identify a mitogen-activated protein kinase (MAPK) cascade, MAPK KINASE 3 (MKK3)-MAPK 6 (MPK6), which is activated by JA in Arabidopsis. We also show that JA negatively controls ATMYC2/JIN1 expression, based on quantitative RT-PCR and genetic analyses using gain-of-function and loss-of-function mutants of the MKK3-MPK6 cascade. These results indicate that this kinase unit plays a key role in JA-dependent negative regulation of ATMYC2/JIN1 expression. Both positive and negative regulation by JA may be used to fine-tune ATMYC2/JIN1 expression to control JA signaling. Moreover, JA-regulated root growth inhibition is affected by mutations in the MKK3-MPK6 cascade, which indicates important roles in JA signaling. We provide a model explaining how MPK6 can convert three distinct signals - JA, pathogen, and cold/salt stress - into three different sets of responses in Arabidopsis.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 5
Claim · model-written summary
Jasmonic acid activated the MKK3–MPK6 cascade in Arabidopsis.
- Taxon
- Arabidopsis
Arabidopsise0 - Treatment
- JAe0
- Gene
- MKK3)-MAPK 6 (MPK6e0
- Outcome
- activatede0
- Direction
- activatede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Arabidopsis”
e0“MAPK KINASE 3 (MKK3)-MAPK 6 (MPK6), which is activated by JA in Arabidopsis.”
Claim · model-written summary
Jasmonic acid negatively controlled ATMYC2/JIN1 expression.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- JAe0
- Gene
- ATMYC2/JIN1e0
- Outcome
- ATMYC2/JIN1 expressione0
- Direction
- negatively controlse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Arabidopsis”
e0“JA negatively controls ATMYC2/JIN1 expression, based on quantitative RT-PCR and genetic analyses using gain-of-function and loss-of-function mutants of the MKK3-MPK6 cascade.”
Claim · model-written summary
The MKK3–MPK6 kinase unit has a key role in jasmonate-dependent negative regulation of ATMYC2/JIN1 expression.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- ATMYC2/JIN1e0
- Outcome
- JA-dependent negative regulation of ATMYC2/JIN1 expressione0
- Qualifier
- this kinase unite0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Arabidopsis”
e0“this kinase unit plays a key role in JA-dependent negative regulation of ATMYC2/JIN1 expression.”
Claim · model-written summary
MKK3–MPK6 mutations affected jasmonate-regulated root growth inhibition.
- Taxon
- ArabidopsisArabidopsist0
- Organ / stage
- roote0
- Treatment
- mutations in the MKK3-MPK6 cascadee0
- Gene
- MKK3-MPK6 cascadee0
- Outcome
- JA-regulated root growth inhibitione0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Arabidopsis”
e0“JA-regulated root growth inhibition is affected by mutations in the MKK3-MPK6 cascade”
Claim · model-written summary
The authors provided a model for how MPK6 converts jasmonate, pathogen, and cold or salt signals into distinct responses.
- Taxon
- ArabidopsisArabidopsise0
- Gene
- MPK6e0
- Outcome
- three different sets of responsese0
Not reportedComparatorValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Arabidopsis”
e0“We provide a model explaining how MPK6 can convert three distinct signals - JA, pathogen, and cold/salt stress - into three different sets of responses in Arabidopsis.”
The same questions in other papers
jasmonic acid · molecular: expression · ArabidopsisPositive and negative results
12 papers in the same direction as this paper · 21 in the opposite direction
- positive
- positive
- positive
30 papers more in this group
See all 34 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.