Abstract
The fermentation conditions for the production of validamycin by Streptomyces hygroscopicus var. limoneus No. T-7545 were studied. Validamycins A and B showed no antimicrobial activity on agar media against bacteria, yeasts and fungi, but caused an abnormal branching at the tips of the hyphae of Pellicularia sasakii. Although they were inactive in vitro, validamycins A and B controlled the sheath blight of rice plants and the damping off of cucumber seedlings in green house tests. Validamycin A was effective against the sheath blight at a concentration of 30ppm. Both antibiotics showed low toxicity to plants, fishes and mice.
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Claims 4
Claim · model-written summary
Validamycins A and B controlled sheath blight of rice plants in greenhouse tests.
- Taxon
- rice plants
Oryza sativae0 - Treatment
- validamycins A and Be0
- Outcome
- sheath blighte0
- Direction
- controllede0
- Setting
- green house testse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Although they were inactive in vitro, validamycins A and B controlled the sheath blight of rice plants and the damping off of cucumber seedlings in green house tests.”
Claim · model-written summary
Validamycins A and B controlled damping off of cucumber seedlings in greenhouse tests.
- Taxon
- cucumber seedlings
Cucumis sativuse0 - Treatment
- validamycins A and Be0
- Outcome
- damping offe0
- Direction
- controllede0
- Setting
- green house testse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Although they were inactive in vitro, validamycins A and B controlled the sheath blight of rice plants and the damping off of cucumber seedlings in green house tests.”
Claim · model-written summary
Validamycin A was effective against sheath blight at 30ppm.
- Taxon
- rice plantsOryza sativae1
- Treatment
- Validamycin Ae0
- Outcome
- sheath blighte0
- Direction
- effectivee0
- Value
- 30ppme0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Validamycin A was effective against the sheath blight at a concentration of 30ppm.”
e1“rice plants”
Claim · model-written summary
Validamycins A and B showed low toxicity to plants.
- Taxon
- plantsViridiplantaee0
- Treatment
- validamycins A and Be1
- Outcome
- toxicity to plantse0
- Direction
- lowe0
Verbatim
e0“Both antibiotics showed low toxicity to plants, fishes and mice.”
e1“validamycins A and B controlled the sheath blight of rice plants”
The same questions in other papers
validamycin A · disease · Oryza sativa (rice)Results agree
7 papers in the same direction as this paper
- positive
- positive
- positive
4 papers more in this group
See all 8 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.