Abstract
Programmed cell death has been associated with plant immunity and senescence. The receptor kinase XA21 confers resistance to bacterial blight disease of rice (Oryza sativa) caused by Xanthomonas oryzae pv. oryzae (Xoo). Here we show that the XA21 binding protein 3 (XB3) is capable of inducing cell death when overexpressed in Nicotiana benthamiana. XB3 is a RING finger-containing E3 ubiquitin ligase that has been positively implicated in XA21-mediated resistance. Mutation abolishing the XB3 E3 activity also eliminates its ability to induce cell death. Phylogenetic analysis of XB3-related sequences suggests a family of proteins (XB3 family) with members from diverse plant species. We further demonstrate that members of the XB3 family from rice, Arabidopsis and citrus all trigger a similar cell death response in Nicotiana benthamiana, suggesting an evolutionarily conserved role for these proteins in regulating programmed cell death in the plant kingdom.
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Claims 6
Claim · model-written summary
Overexpressed XB3 induces cell death in Nicotiana benthamiana.
- Taxon
- Nicotiana benthamiana
Nicotiana benthamianae0 - Treatment
- overexpressede0
- Gene
- XB3e0
- Outcome
- cell deathe0
- Direction
- inducinge0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“XA21 binding protein 3 (XB3) is capable of inducing cell death when overexpressed in Nicotiana benthamiana”
Claim · model-written summary
A mutation abolishing XB3 E3 activity also eliminates cell-death induction.
- Taxon
- Nicotiana benthamianaNicotiana benthamianat0
- Treatment
- Mutation abolishing the XB3 E3 activitye0
- Gene
- XB3e0
- Outcome
- ability to induce cell deathe0
- Direction
- eliminatese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Mutation abolishing the XB3 E3 activity also eliminates its ability to induce cell death.”
t0“Nicotiana benthamiana”
Claim · model-written summary
Phylogenetic analysis supports an XB3-related protein family across diverse plant species.
Verbatim
e0“Phylogenetic analysis of XB3-related sequences suggests a family of proteins (XB3 family) with members from diverse plant species.”
Claim · model-written summary
Rice XB3 family members trigger a similar cell death response in Nicotiana benthamiana.
- Taxon
- Nicotiana benthamianaNicotiana benthamianae0
- Treatment
- members of the XB3 family from ricee0
- Gene
- XB3 familye0
- Outcome
- cell death responsee0
- Direction
- triggere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“members of the XB3 family from rice, Arabidopsis and citrus all trigger a similar cell death response in Nicotiana benthamiana”
Claim · model-written summary
Arabidopsis XB3 family members trigger a similar cell death response in Nicotiana benthamiana.
- Taxon
- Nicotiana benthamianaNicotiana benthamianae0
- Treatment
- members of the XB3 family from rice, Arabidopsis and citruse0
- Gene
- XB3 familye0
- Outcome
- cell death responsee0
- Direction
- triggere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“members of the XB3 family from rice, Arabidopsis and citrus all trigger a similar cell death response in Nicotiana benthamiana”
Claim · model-written summary
Citrus XB3 family members trigger a similar cell death response in Nicotiana benthamiana.
- Taxon
- Nicotiana benthamianaNicotiana benthamianae0
- Treatment
- members of the XB3 family from rice, Arabidopsis and citruse0
- Gene
- XB3 familye0
- Outcome
- cell death responsee0
- Direction
- triggere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“members of the XB3 family from rice, Arabidopsis and citrus all trigger a similar cell death response in Nicotiana benthamiana”
The same questions in other papers
Arabidopsis · cytology · Nicotiana benthamianaPositive and negative results
1 in the opposite direction
- positive
loss of function · cytology · Nicotiana benthamianaPositive and negative results
8 papers in the same direction as this paper · 24 in the opposite direction
- negative
- negative
- negative
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See all 33 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.