Abstract
A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model. UCBPP-PA14 exhibits ecotype specificity for Arabidopsis, causing a range of symptoms from none to severe in four different ecotypes. In the mouse model, UCBPP-PA14 is as lethal as other well-studied P. aeruginosa strains. Mutations in the UCBPP-PA14 toxA, plcS, and gacA genes resulted in a significant reduction in pathogenicity in both hosts, indicating that these genes encode virulence factors required for the full expression of pathogenicity in both plants and animals.
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Claims 4
Claim · model-written summary
P. aeruginosa strain UCBPP-PA14 is infectious in an Arabidopsis thaliana leaf infiltration model.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae0 - Interactor
- Pseudomonas aeruginosa
Pseudomonas aeruginosae0pathogen - Outcome
- infectiouse0
- Setting
- leaf infiltration modele0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model”
Claim · model-written summary
UCBPP-PA14 causes a range of symptoms from none to severe on Arabidopsis, depending on ecotype.
- Taxon
- ArabidopsisArabidopsise1
- Material
- ecotypese1
- Interactor
- UCBPP-PA14e1pathogen
- Outcome
- range of symptomse1
- Qualifier
- from none to severe in four different ecotypese1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“UCBPP-PA14 exhibits ecotype specificity for Arabidopsis, causing a range of symptoms from none to severe in four different ecotypes”
Claim · model-written summary
UCBPP-PA14 is as lethal in mice as other well-studied P. aeruginosa strains.
- Taxon
- Arabidopsis thalianaArabidopsis thalianae0
- Outcome
- lethale2
- Comparator
- other well-studied P. aeruginosa strainse2
MusOrganisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model”
e2“In the mouse model, UCBPP-PA14 is as lethal as other well-studied P. aeruginosa strains”
Claim · model-written summary
Mutations in toxA, plcS and gacA significantly reduced UCBPP-PA14 pathogenicity in both Arabidopsis and mouse hosts.
- Taxon
- Arabidopsis thalianaArabidopsis thalianae0
- Treatment
- Mutations in the UCBPP-PA14 toxA, plcS, and gacA genese3
- Interactor
- UCBPP-PA14e3pathogen
- Gene
- toxA, plcS, and gacAe3
- Outcome
- pathogenicitye3
- Direction
- reductione3
- Qualifier
- in both hostse3
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model”
e3“Mutations in the UCBPP-PA14 toxA, plcS, and gacA genes resulted in a significant reduction in pathogenicity in both hosts”
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