Abstract
L.), the fourth most important food crop worldwide, serves as a multi-purpose resource for food, feed and industrial raw materials, and plays a pivotal role in safeguarding food security, diversifying dietary structure and boosting the development of agricultural economy. With increasing consumer demand for nutritional quality, elucidating the regulatory mechanisms of potato quality traits has become a research priority. In this study, three potato cultivars with distinct coloration were employed as materials. Metabolomic profiling identified a total of 1128 metabolites, and revealed that pigmented potato cultivars accumulated higher levels of flavonoids and linoleic acid derivatives compared with the white-fleshed cultivar. Transcriptomic analysis uncovered numerous differentially expressed genes (DEGs) among the three cultivars; notably, DEGs in pigmented cultivars were significantly enriched in pathways related to terpenoid backbone biosynthesis, flavonoid biosynthesis, linoleic acid metabolism, and starch and sucrose metabolism. Integrated multi-omics analysis revealed that the high expression of structural genes in the flavonoid biosynthesis pathway is strongly associated with flavonoid accumulation in pigmented potatoes, suggesting that transcriptional upregulation of these genes may be a key driver of flavonoid biosynthesis. Furthermore, several MYB and WD40 family transcription factors were identified as potential regulators of flavonoid and anthocyanin biosynthesis in potato. Collectively, our study provides insight into the regulatory mechanisms underlying the biosynthesis of secondary metabolites in potato by combining transcriptomic and metabolomic approaches, and the findings provide a valuable theoretical basis for the genetic improvement of potato nutritional quality in future breeding programs.
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Claims 8
Claim · model-written summary
Metabolomic profiling of the three potato cultivars identified a total of 1128 metabolites.
- Taxon
- potato
Solanum tuberosume1 - Material
- three potato cultivars with distinct coloratione1
- Outcome
- metabolitese0
- Value
- 1128e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Metabolomic profiling identified a total of 1128 metabolites”
e1“three potato cultivars with distinct coloration”
Claim · model-written summary
Pigmented potato cultivars accumulated higher levels of flavonoids and linoleic acid derivatives than the white-fleshed cultivar.
- Taxon
- potatoSolanum tuberosume0
- Material
- pigmented potato cultivarse0
- Outcome
- flavonoids and linoleic acid derivativese0
- Direction
- highere0
- Comparator
- white-fleshed cultivare0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“pigmented potato cultivars accumulated higher levels of flavonoids and linoleic acid derivatives compared with the white-fleshed cultivar”
Claim · model-written summary
Transcriptomic analysis found numerous differentially expressed genes among the three potato cultivars.
- Taxon
- potatoSolanum tuberosume1
- Material
- three potato cultivars with distinct coloratione1
- Outcome
- differentially expressed genes (DEGs)e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Transcriptomic analysis uncovered numerous differentially expressed genes (DEGs) among the three cultivars”
e1“three potato cultivars with distinct coloration”
Claim · model-written summary
DEGs in pigmented cultivars were significantly enriched in terpenoid backbone biosynthesis and flavonoid biosynthesis pathways.
- Taxon
- potatoSolanum tuberosume1
- Outcome
- pathways related to terpenoid backbone biosynthesis, flavonoid biosynthesise0
- Direction
- enrichede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“DEGs in pigmented cultivars were significantly enriched in pathways related to terpenoid backbone biosynthesis, flavonoid biosynthesis, linoleic acid metabolism, and starch and sucrose metabolism”
e1“three potato cultivars with distinct coloration”
Claim · model-written summary
DEGs in pigmented cultivars were significantly enriched in linoleic acid metabolism and starch and sucrose metabolism pathways.
- Taxon
- potatoSolanum tuberosume1
- Outcome
- linoleic acid metabolism, and starch and sucrose metabolisme0
- Direction
- enrichede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“DEGs in pigmented cultivars were significantly enriched in pathways related to terpenoid backbone biosynthesis, flavonoid biosynthesis, linoleic acid metabolism, and starch and sucrose metabolism”
e1“three potato cultivars with distinct coloration”
Claim · model-written summary
High expression of structural genes in the flavonoid biosynthesis pathway is strongly associated with flavonoid accumulation in pigmented potatoes.
- Taxon
- potatoesSolanum tuberosume0
- Gene
- structural genes in the flavonoid biosynthesis pathwaye0
- Outcome
- flavonoid accumulatione0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“high expression of structural genes in the flavonoid biosynthesis pathway is strongly associated with flavonoid accumulation in pigmented potatoes”
Claim · model-written summary
Transcriptional upregulation of these structural genes may be a key driver of flavonoid biosynthesis in pigmented potatoes.
- Taxon
- potatoesSolanum tuberosume0
- Outcome
- flavonoid biosynthesise1
- Qualifier
- transcriptional upregulation of these genese1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“high expression of structural genes in the flavonoid biosynthesis pathway is strongly associated with flavonoid accumulation in pigmented potatoes”
e1“transcriptional upregulation of these genes may be a key driver of flavonoid biosynthesis”
Claim · model-written summary
Several MYB and WD40 family transcription factors were identified as potential regulators of flavonoid and anthocyanin biosynthesis in potato.
- Taxon
- potatoSolanum tuberosume0
- Gene
- MYB and WD40 family transcription factorse0
- Outcome
- potential regulators of flavonoid and anthocyanin biosynthesise0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“several MYB and WD40 family transcription factors were identified as potential regulators of flavonoid and anthocyanin biosynthesis in potato”