Abstract
Facing harsher losses of crop yield due to virus infection, it is critical to reduce yield loss by improving plants’ disease resistance. Here, we proposed using nanoparticles to prestimulate Nicotiana benthamiana as a nanomediated brassinolide (BR) hormone replacement therapy to trigger immune responses and subsequently increase plant immunity against viruses. Our results showed the prestimulated leaves of zinc oxide nanoparticles (ZnONPs) exhibit accelerated antiviral capability, and the plant resistance activation was increased with a decrease in the ZnONP size. Transcriptome data and hormone assays revealed that ZnONP stimulation activated the brassinolide hormone signaling pathway and increased the brassinolide concentration. Importantly, the induced activity of ZnONPs on antiviral capability could be eliminated by virus-mediated silencing of key genes of brassinolide in Nicotiana benthamiana . In summary, we showed prestimulated plants with ZnONPs induced systemic resistance to TMV by activating the brassinolide pathways. This simple nanostimulant-based hormone replacement therapy may alleviate pathogen infection in crop plants and reduce the need for pesticides.
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Claims 7
Claim · model-written summary
ZnONP prestimulation accelerated antiviral capability in Nicotiana benthamiana leaves.
- Taxon
- Nicotiana benthamiana
Nicotiana benthamianat0 - Organ / stage
- leavese0
- Treatment
- zinc oxide nanoparticles (ZnONPs)e0
- Outcome
- antiviral capabilitye0
- Direction
- acceleratede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“prestimulated leaves of zinc oxide nanoparticles (ZnONPs) exhibit accelerated antiviral capability”
t0“prestimulate Nicotiana benthamiana as a nanomediated”
Claim · model-written summary
Plant resistance activation increased as ZnONP size decreased.
- Taxon
- Nicotiana benthamianaNicotiana benthamianat0
- Treatment
- ZnONP sizee0
- Outcome
- plant resistance activatione0
- Direction
- increasede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the plant resistance activation was increased with a decrease in the ZnONP size”
t0“prestimulate Nicotiana benthamiana as a nanomediated”
Claim · model-written summary
ZnONP stimulation activated the brassinolide hormone signaling pathway.
- Taxon
- Nicotiana benthamianaNicotiana benthamianat0
- Treatment
- ZnONP stimulatione0
- Outcome
- brassinolide hormone signaling pathwaye0
- Direction
- activatede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“ZnONP stimulation activated the brassinolide hormone signaling pathway”
t0“prestimulate Nicotiana benthamiana as a nanomediated”
Claim · model-written summary
ZnONP stimulation increased brassinolide concentration.
- Taxon
- Nicotiana benthamianaNicotiana benthamianat0
- Treatment
- ZnONP stimulatione0
- Outcome
- brassinolide concentratione0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“ZnONP stimulation activated the brassinolide hormone signaling pathway and increased the brassinolide concentration”
t0“prestimulate Nicotiana benthamiana as a nanomediated”
Claim · model-written summary
Silencing key brassinolide genes eliminated the ZnONP-induced antiviral capability.
- Taxon
- Nicotiana benthamianaNicotiana benthamianae0
- Treatment
- virus-mediated silencing of key genes of brassinolidee0
- Gene
- key genes of brassinolidee0
- Outcome
- antiviral capabilitye0
- Direction
- eliminatede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the induced activity of ZnONPs on antiviral capability could be eliminated by virus-mediated silencing of key genes of brassinolide in Nicotiana benthamiana”
Claim · model-written summary
ZnONP prestimulation induced systemic resistance to TMV through activation of brassinolide pathways.
- Taxon
- Nicotiana benthamianaNicotiana benthamianat0
- Treatment
- ZnONPse0
- Interactor
- TMV
Tobacco mosaic viruse0pathogen - Outcome
- systemic resistance to TMVe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“prestimulated plants with ZnONPs induced systemic resistance to TMV by activating the brassinolide pathways”
t0“prestimulate Nicotiana benthamiana as a nanomediated”
Claim · model-written summary
The authors suggest ZnONP-based stimulation may alleviate crop plant pathogen infection and reduce pesticide needs.
Verbatim
e0“This simple nanostimulant-based hormone replacement therapy may alleviate pathogen infection in crop plants and reduce the need for pesticides”
The same questions in other papers
loss of function · molecular: metabolites · Nicotiana benthamianaPositive and negative results
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See all 35 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.