Abstract
Defects in cell wall integrity (CWI) profoundly affect plant growth, although, underlying mechanisms are not well understood. We show that in Arabidopsis mur1 mutant, CWI defects from compromising dimerization of RG-II pectin, a key component of cell wall, attenuate the expression of auxin response factors ARF7-ARF19 . As a result, polar auxin transport components are misexpressed, disrupting auxin response asymmetry, leading to defective apical hook development. Accordingly, mur1 hook defects are suppressed by enhancing ARF7 expression. In addition, expression of brassinosteroid biosynthesis genes is down-regulated in mur1 mutant, and supplementing brassinosteroid or enhancing brassinosteroid signaling suppresses mur1 hook defects. Intriguingly, brassinosteroid enhances RG-II dimerization, showing hormonal feedback to the cell wall. Our results thus reveal a previously unrecognized link between cell wall defects from reduced RG-II dimerization and growth regulation mediated via modulation of auxin-brassinosteroid pathways in early seedling development.
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Claims 9
Claim · model-written summary
Compromised RG-II dimerization in mur1 attenuates ARF7-ARF19 expression.
- Taxon
- Arabidopsis
Arabidopsise0 - Material
- mur1 mutante0
- Gene
- auxin response factors ARF7-ARF19e0
- Outcome
- expression of auxin response factors ARF7-ARF19e0
- Direction
- attenuatee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“in Arabidopsis mur1 mutant, CWI defects from compromising dimerization of RG-II pectin, a key component of cell wall, attenuate the expression of auxin response factors ARF7-ARF19”
Claim · model-written summary
Polar auxin transport components are misexpressed in mur1.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante1
- Outcome
- polar auxin transport components are misexpressede0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“As a result, polar auxin transport components are misexpressed”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Auxin response asymmetry is disrupted in mur1.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante1
- Outcome
- auxin response asymmetrye0
- Direction
- disruptinge0
- Qualifier
- defective apical hook developmente0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“disrupting auxin response asymmetry, leading to defective apical hook development”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Disrupted auxin response asymmetry leads to defective apical hook development in mur1.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante1
- Outcome
- defective apical hook developmente0
- Qualifier
- auxin response asymmetrye0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“disrupting auxin response asymmetry, leading to defective apical hook development”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Enhancing ARF7 expression suppresses mur1 hook defects.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante1
- Treatment
- enhancing ARF7 expressione0
- Gene
- ARF7e0
- Outcome
- mur1 hook defectse0
- Direction
- suppressede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“mur1 hook defects are suppressed by enhancing ARF7 expression”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Brassinosteroid biosynthesis gene expression is down-regulated in mur1.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante0
- Gene
- brassinosteroid biosynthesis genese0
- Outcome
- expression of brassinosteroid biosynthesis genese0
- Direction
- down-regulatede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“expression of brassinosteroid biosynthesis genes is down-regulated in mur1 mutant”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Supplementing brassinosteroid suppresses mur1 hook defects.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante1
- Treatment
- supplementing brassinosteroide0
- Outcome
- mur1 hook defectse0
- Direction
- suppressese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“supplementing brassinosteroid or enhancing brassinosteroid signaling suppresses mur1 hook defects”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Enhancing brassinosteroid signaling suppresses mur1 hook defects.
- Taxon
- ArabidopsisArabidopsise1
- Material
- mur1 mutante1
- Treatment
- enhancing brassinosteroid signalinge0
- Outcome
- mur1 hook defectse0
- Direction
- suppressese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“supplementing brassinosteroid or enhancing brassinosteroid signaling suppresses mur1 hook defects”
e1“in Arabidopsis mur1 mutant”
Claim · model-written summary
Brassinosteroid enhances RG-II dimerization.
- Taxon
- ArabidopsisArabidopsise1
- Treatment
- brassinosteroide0
- Outcome
- RG-II dimerizatione0
- Direction
- enhancese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“brassinosteroid enhances RG-II dimerization”
e1“in Arabidopsis mur1 mutant”
The same questions in other papers
class · molecular: metabolites · ArabidopsisPositive and negative results
6 papers in the same direction as this paper · 5 in the opposite direction
- positive
- no effect
- no effect
8 papers more in this group
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