Abstract
This study explores the therapeutic potential of Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment. Traditionally used in Ayurveda, these plants are rich in bioactive compounds. Ethanolic extracts were assessed for phytochemical content, antioxidant, and anti-inflammatory properties. Thin-layer chromatography (TLC) confirmed the presence of flavonoids, phenolics, tannins, saponins, terpenoids, steroids, glycosides, and alkaloids. Total phenolics and flavonoids were quantified using colorimetric assays. Antioxidant activity was evaluated through total antioxidant capacity (TAC) and ferric reducing power (FRAP) assays. Anti-inflammatory activity was assessed via albumin denaturation inhibition, anti-protease activity, and membrane stabilization assays. Antibacterial efficacy against Bacillus subtilis and Escherichia coli was tested using agar well diffusion. Guava extract exhibited higher total phenolic content (121.6 mg GAE/g) and comparable flavonoid content (280 mg QE/g) to Chameli. Both extracts demonstrated notable antioxidant activity, with Guava showing superior anti-inflammatory effects across all assays and antibacterial activity against both bacterial strains. These findings highlight the bioactive compounds contributing to the therapeutic potential of Guava and Chameli leaves. The developed herbal oral paste was effective in promoting healing, supporting its potential for oral ulcer treatment, although further clinical validation is needed.
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Claims 8
Claim · model-written summary
Guava extract had higher total phenolic content, 121.6 mg GAE/g, than chameli.
- Taxon
- Psidium guajava
Psidium guajavae0 - Treatment
- Guava extracte1
- Outcome
- total phenolic contente1
- Direction
- highere1
- Value
- 121.6 mg GAE/ge1
- Comparator
- Chamelie1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e1“Guava extract exhibited higher total phenolic content (121.6 mg GAE/g) and comparable flavonoid content (280 mg QE/g) to Chameli”
Claim · model-written summary
Guava extract had flavonoid content comparable to chameli, 280 mg QE/g.
- Taxon
- Psidium guajavaPsidium guajavae0
- Treatment
- Guava extracte1
- Outcome
- flavonoid contente1
- Direction
- comparablee1
- Value
- 280 mg QE/ge1
- Comparator
- Chamelie1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e1“Guava extract exhibited higher total phenolic content (121.6 mg GAE/g) and comparable flavonoid content (280 mg QE/g) to Chameli”
Claim · model-written summary
Guava extract demonstrated notable antioxidant activity.
- Taxon
- Psidium guajavaPsidium guajavae0
- Outcome
- antioxidant activitye2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e2“Both extracts demonstrated notable antioxidant activity”
Claim · model-written summary
Chameli extract demonstrated notable antioxidant activity.
- Taxon
- Jasminum grandiflorum
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Jasminum grandiflorume0 - Outcome
- antioxidant activitye2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e2“Both extracts demonstrated notable antioxidant activity”
Claim · model-written summary
Guava showed superior anti-inflammatory effects across all assays.
- Taxon
- Psidium guajavaPsidium guajavae0
- Outcome
- anti-inflammatory effectse3
- Direction
- superiore3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e3“Guava showing superior anti-inflammatory effects across all assays and antibacterial activity against both bacterial strains”
Claim · model-written summary
Guava showed antibacterial activity against both bacterial strains tested.
- Taxon
- Psidium guajavaPsidium guajavae0
- Outcome
- antibacterial activitye3
- Qualifier
- against both bacterial strainse3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e3“Guava showing superior anti-inflammatory effects across all assays and antibacterial activity against both bacterial strains”
Claim · model-written summary
The developed herbal oral paste increased healing.
- Taxon
- Psidium guajava (Guava) and Jasminum grandiflorum (Chameli)Psidium guajavaJasminum grandiflorume0
- Treatment
- herbal oral pastee5
- Outcome
- healinge5
- Direction
- increaseinferrede5
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e5“The developed herbal oral paste was effective in promoting healing”
Claim · model-written summary
Guava and chameli leaves contain alkaloids, flavonoids, phenolics, tannins, saponins, terpenoids, steroids and glycosides.
- Taxon
- Psidium guajava (Guava) and Jasminum grandiflorum (Chameli)Psidium guajavaJasminum grandiflorume0
- Outcome
- presence of flavonoids, phenolics, tannins, saponins, terpenoids, steroids, glycosides, and alkaloidse6
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Psidium guajava (Guava) and Jasminum grandiflorum (Chameli) leaves for oral ulcer treatment”
e6“Thin-layer chromatography (TLC) confirmed the presence of flavonoids, phenolics, tannins, saponins, terpenoids, steroids, glycosides, and alkaloids”
The same questions in other papers
botanical · quality: phytochemicals · Psidium guajava (guava)Results agree
6 papers in the same direction as this paper
- positive
- positive
- positive
3 papers more in this group
See all 7 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.