Abstract
Currently, the arsenal of the pharmaceutical market has significantly expanded with highly effective drugs of plant origin. More than 1000 essential-oil-bearing plants grow in the flora of Kazakhstan. Of great interest are some species from the families Lamiaceae, Apiaceae, Asteraceae, which have not been studied at all before, or for which there is only brief information about the chemical composition and biological properties. In this respect, the Lamiaceae L. family, which is one of the leading in the flora of Kazakhstan, is of interest. So, on the territory of the republic in this family, there are 233 species, united in 45 genera. Among them, the most famous are plants of the genus Dracocephalum, which are a rich and very common source of essential oils. The aim of the study was to investigate volatile compounds from the aerial parts of Dracocephalum nutans L. of the genus Dracocephalum of the family Lamiaceae grown wild in Central Kazakhstan. D. nutans – perennial with a beautiful purple flower. Materials and methods. The aim of the study was to study volatile compounds from the aerial parts of Dracocephalum nutans L. of the genus Dracocephalum, Lamiaceae family grown wild in Central Kazakhstan. The oils were obtained using Clevenger apparatus, their composition was evaluated by means of gas chromatography/mass spectrometry (GC/MS). The antibacterial activity of D.nutans essential oil sample was assessed by the diameter of the growth inhibition zones of the test strains (mm). Results and Discussion. The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%). The results obtained showed differences in the composition of essential oils obtained from already studied D. nutans. 1.8-cineol was also found in D. nutans as one of the major component. Conclusion. As a result of a study on antimicrobial activity, it was established for the first time that a sample of D. nutans essential oil exhibited pronounced antimicrobial activity against strains of gram-positive bacteria Staphylococcus aureus, Bacillus subtilis and weak antimicrobial activity against gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa.
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Claims 11
Claim · model-written summary
D.nutans essential oil contained 34% 1.8-cineol.
- Taxon
- D.nutans
_(542795795).jpg?width=60)
Dracocephalum nutanse0 - Outcome
- 1.8-cineole0
- Value
- 34%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_(542795795).jpg?width=500)
Verbatim
e0“The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%).”
Claim · model-written summary
D.nutans essential oil contained 6.7% α-pinene.
- Taxon
- D.nutansDracocephalum nutanse0
- Outcome
- α-pinenee0
- Value
- 6.7%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%).”
Claim · model-written summary
D.nutans essential oil contained 5.2% β-pinene.
- Taxon
- D.nutansDracocephalum nutanse0
- Outcome
- β-pinenee0
- Value
- 5.2%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%).”
Claim · model-written summary
D.nutans essential oil contained 5.3% β-mircene.
- Taxon
- D.nutansDracocephalum nutanse0
- Outcome
- β-mircenee0
- Value
- 5.3%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%).”
Claim · model-written summary
D.nutans essential oil contained 8.0% α-thujone.
- Taxon
- D.nutansDracocephalum nutanse0
- Outcome
- α-thujonee0
- Value
- 8.0%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%).”
Claim · model-written summary
D.nutans essential oil contained 5.3% β-thujone.
- Taxon
- D.nutansDracocephalum nutanse0
- Outcome
- β-thujonee0
- Value
- 5.3%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The main natural components of D.nutans essential oil were 1.8-cineol (34%), α-pinene (6.7%), β-pinene (5.2%), β-mircene (5.3%), α-thujone (8.0%) and β-thujone (5.3%).”
Claim · model-written summary
Essential oil composition differed from previously studied D. nutans oils.
- Taxon
- D. nutansDracocephalum nutanse0
- Outcome
- composition of essential oilse0
- Direction
- differencese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The results obtained showed differences in the composition of essential oils obtained from already studied D. nutans.”
Claim · model-written summary
The oil exhibited pronounced antimicrobial activity against Staphylococcus aureus.
- Taxon
- Staphylococcus aureus
Staphylococcus aureuse0 - Treatment
- D. nutans essential oile0
- Outcome
- antimicrobial activitye0
- Qualifier
- pronouncede0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a sample of D. nutans essential oil exhibited pronounced antimicrobial activity against strains of gram-positive bacteria Staphylococcus aureus, Bacillus subtilis and weak antimicrobial activity against gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa.”
Claim · model-written summary
The oil exhibited pronounced antimicrobial activity against Bacillus subtilis.
- Taxon
- Bacillus subtilis
Bacillus subtilise0 - Treatment
- D. nutans essential oile0
- Outcome
- antimicrobial activitye0
- Qualifier
- pronouncede0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a sample of D. nutans essential oil exhibited pronounced antimicrobial activity against strains of gram-positive bacteria Staphylococcus aureus, Bacillus subtilis and weak antimicrobial activity against gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa.”
Claim · model-written summary
The oil exhibited weak antimicrobial activity against Escherichia coli.
- Taxon
- Escherichia coli
.jpg?width=60)
Escherichia colie0 - Treatment
- D. nutans essential oile0
- Outcome
- antimicrobial activitye0
- Qualifier
- weake0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
e0“a sample of D. nutans essential oil exhibited pronounced antimicrobial activity against strains of gram-positive bacteria Staphylococcus aureus, Bacillus subtilis and weak antimicrobial activity against gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa.”
Claim · model-written summary
The oil exhibited weak antimicrobial activity against Pseudomonas aeruginosa.
- Taxon
- Pseudomonas aeruginosa
Pseudomonas aeruginosae0 - Treatment
- D. nutans essential oile0
- Outcome
- antimicrobial activitye0
- Qualifier
- weake0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a sample of D. nutans essential oil exhibited pronounced antimicrobial activity against strains of gram-positive bacteria Staphylococcus aureus, Bacillus subtilis and weak antimicrobial activity against gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa.”
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See all 15 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.