Paper · 2023 · Nigerian Journal of Chemical Research

Phytochemistry, Proximate Analysis and Acute Toxicity Study of Ethanolic Moringa Oleifera Root Bark Extract.

C D Nimyel; J A Lori

4
claims
8
verbatim quotes
3
citations
2
research areas
✓
Open access

Abstract

Moringa Oleifera is a fast growing deciduous tree with its different plant parts commonly used in herbal medicine, also with good socio-economic and industrial values. The ethanolic extract of M.Oleifera root bark is shown to be rich in nutrients, owing to the presence of essential phytochemicals in the root bark. The phytochemicals or secondary metabolites of the ethanolic extract of the root bark were screened and identified. Also, acute toxicity study of the ethanolic extract of the root bark was carriedout in Albino Rats according to Institutional Animal Care and Use (IACU) guidelines. The fresh M.Oleifera root was harvested at the inception of the rainy season at Pil Gani District of Langtang North LGA and excess soil washed off as the root bark was properly peeled, air dried, pulverized to powdered form and stored for subsequent use. Serial extractions using water, acetone, ethanol, and ethyl acetate were carriedout by Simple Maceration. The ethanolic extract was seen to have the best yield of the phytochemicals qualitatively identified as tannins, saponins, carbohydrates, flavonoids, alkaloids, steroids, terpenes, cardiac glycosides and anthraquinones. Acute toxicity test was determined by Lorke’s method and the LD50 was shown to be at the highest limit dose of 5000mg/kg, which signifies that the extract is non toxic at such single dosage. The ethanolic M.Oleifera root bark extract contains nutritive phytochemicals with vast medicinal uses. No sign of acute toxicity was observed on oral administration as the median lethal dose was shown to be safe at the highest limit single dose of 5000mg/kg.

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Claims 4

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Ethanol gave the best phytochemical yield among the tested solvents.

Taxon
M.Oleiferae1
Organ / stage
root barke1
Treatment
ethanolic extracte0
Outcome
yield of the phytochemicalse0
Direction
beste0

Not reportedComparator

Verbatim

e0

“The ethanolic extract was seen to have the best yield of the phytochemicals”

✓ located verbatim in the source · abstract, characters 958–1033 · show in text ↑
e1

“The ethanolic M.Oleifera root bark extract contains nutritive phytochemicals”

✓ located verbatim in the source · abstract, characters 1369–1445 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Moringa root bark extract contained tannins, saponins and carbohydrates.

Taxon
M.Oleiferae1
Organ / stage
root barke1
Outcome
tannins, saponins, carbohydratese0

Verbatim

e0

“phytochemicals qualitatively identified as tannins, saponins, carbohydrates, flavonoids, alkaloids, steroids, terpenes, cardiac glycosides and anthraquinones”

✓ located verbatim in the source · abstract, characters 1019–1176 · show in text ↑
e1

“The ethanolic M.Oleifera root bark extract contains nutritive phytochemicals”

✓ located verbatim in the source · abstract, characters 1369–1445 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Moringa root bark extract contained flavonoids, alkaloids and steroids.

Taxon
M.Oleiferae1
Organ / stage
root barke1
Outcome
flavonoids, alkaloids, steroidse0

Verbatim

e0

“phytochemicals qualitatively identified as tannins, saponins, carbohydrates, flavonoids, alkaloids, steroids, terpenes, cardiac glycosides and anthraquinones”

✓ located verbatim in the source · abstract, characters 1019–1176 · show in text ↑
e1

“The ethanolic M.Oleifera root bark extract contains nutritive phytochemicals”

✓ located verbatim in the source · abstract, characters 1369–1445 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Moringa root bark extract contained terpenes, cardiac glycosides and anthraquinones.

Taxon
M.Oleiferae1
Organ / stage
root barke1
Outcome
terpenes, cardiac glycosides and anthraquinonese0

Verbatim

e0

“phytochemicals qualitatively identified as tannins, saponins, carbohydrates, flavonoids, alkaloids, steroids, terpenes, cardiac glycosides and anthraquinones”

✓ located verbatim in the source · abstract, characters 1019–1176 · show in text ↑
e1

“The ethanolic M.Oleifera root bark extract contains nutritive phytochemicals”

✓ located verbatim in the source · abstract, characters 1369–1445 · show in text ↑

botanical · yield · Moringa oleifera (horseradish tree)Results agree

3 papers: 3 positive, 0 negative or no effect

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  2. positive
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Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.