Paper · 2023 · International Research Journal of Modernization in Engineering Technology and Science

AROMATASE INHIBITION ACTIVITY OF CITRUS FRUITS AGAINST BREAST CANCER

Faiqa Naveen; Habitha Sri; Gomathi Kannayiram; et al.

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Open access · other-oa

Abstract

Breast cancer is a tumorous growth that develops in mammalian gland-lactating tissue's cell lines. Since aromatase controls how quickly estrogen is produced, it is crucial for treating estrogen-receptor positive breast cancer. The mainstay of treatment continues to be endocrine-based medications, which include aromatase inhibitors and estrogen receptor (ER) modifiers. Several synthetic aromatase inhibitors are now being used in clinical settings to treat hormone-receptor positive breast cancer in postmenopausal women. The hunt for novel aromatase inhibitors, particularly for those, whose activity is promoter-specific and further continues because these treatments could have undesirable side effects.

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