Abstract
The rhizosphere interaction between plant roots or pathogenic microbes is initiated by mutual exchange of signals. However, how soil pathogens sense host signals is largely unknown. Here, we studied early molecular events associated with host recognition in Fusarium graminearum , an economically important fungal pathogen that can infect both roots and heads of cereal crops. We found that host sensing prior to physical contact with plant roots radically alters the transcriptome and triggers nitric oxide (NO) production in F. graminearum . We identified an ankyrin-repeat domain containing protein (FgANK1) required for host-mediated NO production and virulence in F. graminearum . In the absence of host plant, FgANK1 resides in the cytoplasm. In response to host signals, FgANK1 translocates to the nucleus and interacts with a zinc finger transcription factor (FgZC1), also required for specific binding to the nitrate reductase ( NR ) promoter, NO production, and virulence in F. graminearum . Our results reveal mechanistic insights into host-recognition strategies employed by soil pathogens.
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Claims 6
Claim · model-written summary
Host sensing before root contact alters the F. graminearum transcriptome and triggers nitric oxide production.
- Taxon
- F. graminearum
_on_Corn_(Zea_mays)_at_Waimea%2C_Hawaii.jpg?width=60)
Fusarium graminearume0 - Treatment
- host sensinge0
- Interactor
- plante0host
- Outcome
- transcriptomee0
- Qualifier
- prior to physical contact with plant rootse0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_on_Corn_(Zea_mays)_at_Waimea%2C_Hawaii.jpg?width=500)
Verbatim
e0“We found that host sensing prior to physical contact with plant roots radically alters the transcriptome and triggers nitric oxide (NO) production in F. graminearum .”
Claim · model-written summary
Host sensing triggers nitric oxide production in F. graminearum before root contact.
- Taxon
- F. graminearumFusarium graminearume0
- Treatment
- host sensinge0
- Interactor
- plante0host
- Outcome
- nitric oxide (NO) productione0
- Direction
- triggerse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“We found that host sensing prior to physical contact with plant roots radically alters the transcriptome and triggers nitric oxide (NO) production in F. graminearum .”
Claim · model-written summary
FgANK1 is required for host-mediated nitric oxide production and virulence.
- Taxon
- F. graminearumFusarium graminearume0
- Gene
- FgANK1e0
- Outcome
- host-mediated NO production and virulencee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“We identified an ankyrin-repeat domain containing protein (FgANK1) required for host-mediated NO production and virulence in F. graminearum .”
Claim · model-written summary
FgANK1 resides in the cytoplasm without a host plant.
- Taxon
- F. graminearumFusarium graminearume1
- Interactor
- plante0host
- Gene
- FgANK1e0
- Outcome
- resides in the cytoplasme0
- Qualifier
- absence of host plante0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In the absence of host plant, FgANK1 resides in the cytoplasm.”
e1“host-mediated NO production and virulence in F. graminearum .”
Claim · model-written summary
Host signals cause FgANK1 nuclear translocation and interaction with FgZC1.
- Taxon
- F. graminearumFusarium graminearume0
- Treatment
- host signalse0
- Gene
- FgANK1e0
- Outcome
- translocates to the nucleus and interacts with a zinc finger transcription factore0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In response to host signals, FgANK1 translocates to the nucleus and interacts with a zinc finger transcription factor (FgZC1), also required for specific binding to the nitrate reductase ( NR ) promoter, NO production, and virulence in F. graminearum .”
Claim · model-written summary
FgZC1 is required for nitrate reductase promoter binding, NO production, and virulence.
- Taxon
- F. graminearumFusarium graminearume0
- Gene
- FgZC1e0
- Outcome
- specific binding to the nitrate reductase ( NR ) promoter, NO production, and virulencee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a zinc finger transcription factor (FgZC1), also required for specific binding to the nitrate reductase ( NR ) promoter, NO production, and virulence in F. graminearum .”