Paper · 1991 · Weed Science

Efficacy and Mode of Action of CGA-154281, A Protectant for Corn (Zea mays) from Metolachlor Injury

Loston Rowe; James J. Kells; Donald Penner

8
claims
13
verbatim quotes
17
citations
3
research areas
—
Not open access

Abstract

Greenhouse and field studies were conducted to determine the influence of herbicide rate, hybrid variability, and soil moisture on the effectiveness of CGA-154281 in protecting corn seedlings from metolachlor injury. High rates of metolachlor caused significant injury to seedlings of sensitive corn hybrids. However, with metolachlor plus CGA-154281, very few injury symptoms were observed, even with the 7.8 kg ha –1 rate and the most sensitive hybrid. Corn seedlings were not injured by metolachlor plus CGA-154281 at the highest soil moisture level evaluated, whereas those treated with metolachlor alone showed 70% injury. Metolachlor injury increased as soil moisture content increased. In the greenhouse, CGA-154281 did not protect any of the eight weed species tested against injury by 2.2 kg ha –1 metolachlor. In laboratory studies, CGA-154281 did not alter the absorption of 14 C-metolachlor during an 8-h period. Qualitative comparison of the metabolism of metolachlor in the presence or absence of the protectant indicated that metolachlor was metabolized to a more polar metabolite, believed to be a glutathione conjugate. However, CGA-154281 significantly enhanced the rate of metabolism of metolachlor in three of the four hybrids tested. Metolachlor metabolism activity may already have been functioning at a maximum level in the unaffected hybrid.

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Claims 8

Intervention effectobservedoriginal resultnegativesignificant (as stated)measured

Claim · model-written summary

High metolachlor rates significantly injured sensitive corn seedlings.

Organ / stage
seedlingse0
Treatment
High rates of metolachlore0
Outcome
injurye0
Direction
causede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“High rates of metolachlor caused significant injury to seedlings of sensitive corn hybrids.”

✓ located verbatim in the source · abstract, characters 217–308 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Metolachlor plus CGA-154281 yielded very few injury symptoms even at 7.8 kg ha –1 in the most sensitive hybrid.

Treatment
metolachlor plus CGA-154281e0
Outcome
injury symptomse0
Direction
very fewe0
Value
7.8 kg ha –1e0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“with metolachlor plus CGA-154281, very few injury symptoms were observed, even with the 7.8 kg ha –1 rate and the most sensitive hybrid.”

✓ located verbatim in the source · abstract, characters 318–454 · show in text ↑
t0

“Corn (Zea mays)”

✓ located verbatim in the source · title, characters 60–75 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

At the highest soil moisture, metolachlor plus CGA-154281 did not injure corn seedlings, whereas metolachlor alone caused 70% injury.

Treatment
metolachlor plus CGA-154281e0
Outcome
injurede0
Direction
not injurede0
Value
70%e0
Qualifier
highest soil moisture levele0
Comparator
metolachlor alonee0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Corn seedlings were not injured by metolachlor plus CGA-154281 at the highest soil moisture level evaluated, whereas those treated with metolachlor alone showed 70% injury.”

✓ located verbatim in the source · abstract, characters 455–627 · show in text ↑
Associationobservedoriginal resultnegativemeasured

Claim · model-written summary

Metolachlor injury increased with soil moisture content.

Treatment
soil moisture contente0
Outcome
Metolachlor injurye0
Direction
increasede0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Metolachlor injury increased as soil moisture content increased.”

✓ located verbatim in the source · abstract, characters 628–692 · show in text ↑
t0

“Corn (Zea mays)”

✓ located verbatim in the source · title, characters 60–75 · show in text ↑
Intervention effectobservedoriginal resultno effectmeasured

Claim · model-written summary

CGA-154281 did not protect eight weed species from metolachlor injury.

Treatment
CGA-154281e0
Outcome
injurye0
Direction
did not protecte0
Value
2.2 kg ha –1e0
Qualifier
eight weed speciese0

Not reportedTaxonComparator

Verbatim

e0

“CGA-154281 did not protect any of the eight weed species tested against injury by 2.2 kg ha –1 metolachlor.”

✓ located verbatim in the source · abstract, characters 712–819 · show in text ↑
Intervention effectobservedoriginal resultno effectmeasured

Claim · model-written summary

CGA-154281 did not alter 14 C-metolachlor absorption over 8 h.

Treatment
CGA-154281e0
Outcome
absorption of 14 C-metolachlore0
Direction
did not altere0
Qualifier
8-h periode0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“CGA-154281 did not alter the absorption of 14 C-metolachlor during an 8-h period.”

✓ located verbatim in the source · abstract, characters 843–924 · show in text ↑
t0

“Corn (Zea mays)”

✓ located verbatim in the source · title, characters 60–75 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Metolachlor was metabolized to a more polar metabolite believed to be a glutathione conjugate.

Outcome
more polar metabolitee0
Qualifier
believed to be a glutathione conjugatee0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“metolachlor was metabolized to a more polar metabolite, believed to be a glutathione conjugate.”

✓ located verbatim in the source · abstract, characters 1041–1136 · show in text ↑
t0

“Corn (Zea mays)”

✓ located verbatim in the source · title, characters 60–75 · show in text ↑
Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

CGA-154281 significantly enhanced metolachlor metabolism in three of four hybrids.

Treatment
CGA-154281e0
Outcome
rate of metabolism of metolachlore0
Direction
enhancede0
Value
three of the four hybridse0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“CGA-154281 significantly enhanced the rate of metabolism of metolachlor in three of the four hybrids tested.”

✓ located verbatim in the source · abstract, characters 1146–1254 · show in text ↑
t0

“Corn (Zea mays)”

✓ located verbatim in the source · title, characters 60–75 · show in text ↑

metolachlor · crop injury · Zea mays (maize)Positive and negative results

7 papers: 2 positive, 5 negative or no effect

1 paper in the same direction as this paper · 5 in the opposite direction

  1. negative
  2. negative
  3. negative

3 papers more in this group

See all 7 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.