Paper · 2018 · Research & Reviews: Journal of Botany

Cadmium-induced Lipid Peroxidation and DNA Damage in Sorghum Bicolor Seedlings

Manoj Nath; A Srinivasulu; A. Radhaiah; et al.

5
claims
9
verbatim quotes
0
citations
1
research areas
—
Not open access

Abstract

Abstract The effect of cadmium (Cd) on lipid peroxidation and DNA damage was studied in a variety of SP18008 Sorghum bicolor seedlings which were exposed to different concentrations of Cd (0, 25, 50, 75 and 100 μmol/L) heavy metal for two weeks. After two weeks of Cd treatment, Lipid peroxidation was increased in the form of MDA content along with increased concentration of Cd whereas increased DNA damage was also observed in roots of Cd-treated sorghum along with increase in concentration. The higher concentration such as 75 and 100 μmol/L of Cd shows highest lipid peroxidation and the extent of DNA damage. The increase may be, however, associated with necrotic and apoptotic DNA fragmentation, as the affected plants had inhibited growth and distorted yellowish leaves. Keywords: Cadmium, lipid peroxidation, DNA, sorghum bicolor

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Claims 5

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Increasing cadmium concentration increased seedling MDA content.

Taxon
Sorghum bicolorSorghum bicolort0
Treatment
Cde0
Outcome
MDA contente0
Direction
increasede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sorghum bicolor
Sorghum bicolor · TaxonNo machine-readable author provided. Pethan assumed (based on copyright claims). · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Lipid peroxidation was increased in the form of MDA content along with increased concentration of Cd”

✓ located verbatim in the source · abstract, characters 279–379 · show in text ↑
t0

“Sorghum bicolor”

✓ located after whitespace/quote normalisation · title, characters 53–68 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Increasing cadmium concentration increased root DNA damage.

Taxon
sorghumSorghume0
Organ / stage
rootse0
Treatment
Cd-treatede0
Outcome
DNA damagee0
Direction
increasede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sorghum
Sorghum · Taxon · picture of the genus (one of its species)Evelyn Simak · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“increased DNA damage was also observed in roots of Cd-treated sorghum along with increase in concentration”

✓ located verbatim in the source · abstract, characters 388–494 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Cadmium at 75 and 100 μmol/L produced the highest lipid peroxidation.

Taxon
Sorghum bicolorSorghum bicolort0
Treatment
75 and 100 μmol/L of Cde0
Outcome
lipid peroxidatione0
Direction
higheste0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sorghum bicolor
Sorghum bicolor · TaxonNo machine-readable author provided. Pethan assumed (based on copyright claims). · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“75 and 100 μmol/L of Cd shows highest lipid peroxidation”

✓ located verbatim in the source · abstract, characters 529–585 · show in text ↑
t0

“Sorghum bicolor”

✓ located after whitespace/quote normalisation · title, characters 53–68 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Cadmium at 75 and 100 μmol/L produced the highest DNA damage.

Taxon
Sorghum bicolorSorghum bicolort0
Treatment
75 and 100 μmol/L of Cde0
Outcome
DNA damagee0
Direction
higheste0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sorghum bicolor
Sorghum bicolor · TaxonNo machine-readable author provided. Pethan assumed (based on copyright claims). · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“75 and 100 μmol/L of Cd shows highest lipid peroxidation and the extent of DNA damage”

✓ located verbatim in the source · abstract, characters 529–614 · show in text ↑
t0

“Sorghum bicolor”

✓ located after whitespace/quote normalisation · title, characters 53–68 · show in text ↑
Observationobservedoriginal resultnegativemeasured

Claim · model-written summary

Affected plants had inhibited growth and distorted yellowish leaves.

Taxon
Sorghum bicolorSorghum bicolort0
Outcome
inhibited growth and distorted yellowish leavese0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sorghum bicolor
Sorghum bicolor · TaxonNo machine-readable author provided. Pethan assumed (based on copyright claims). · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“the affected plants had inhibited growth and distorted yellowish leaves”

✓ located verbatim in the source · abstract, characters 707–778 · show in text ↑
t0

“Sorghum bicolor”

✓ located after whitespace/quote normalisation · title, characters 53–68 · show in text ↑

cadmium atom · physiology: oxidative · Sorghum bicolor (sorghum)Positive and negative results

4 papers: 1 positive, 3 negative or no effect

2 papers in the same direction as this paper · 1 in the opposite direction

  1. positive
  2. negative
  3. negative
See all 4 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.