Abstract
OBJECTIVE: In this study four tea samples Gumero black, Wushwush black and Wushwush green from Agri- Ceft Plc and East Africa black tea leaves from East African Agribusiness Plc were investigated for total polyphenols, caffeine, catechin and L-theanine content. MATERIALS AND METHODS: The aqueous extracts were investigated for their antioxidant and antileishmanial property and effect on amphotericin B, miltefocine and sodium stibogluconate, the commonly used antileishmanial drugs. Antileishmanial studies were conducted on L. aethiopica. RESULTS: Wushwush green tea had the highest content of polyphenol (19.98 ± 1.15 mg gallic acid equivalent /100 g dry leaf weight), catechin (37.06 mg/g) and L-theanine (48.54 mg/g but the lowest caffeine content). It exhibited the highest antioxidant activity. The highest antioxidant effect of Wushwush green tea may be attributed to the highest polyphenol content. East African black tea had the lowest L-theanine (20.72 mg/g) and antioxidant activity but the highest caffeine (16.60 mg/g) content. CONCLUSION: Wushwush green tea showed slight inhibitory effect on L. aethiopica while the lack tea extracts (Gumero, East Africa and Wushwush) exhibited no antileishmanial activity. Wushwush green tea did not show any synergistic or antagonistic effect on the antileishmanial drugs used in this study while Gumero, East Africa and Wushwush black tea extracts exhibited dose dependant inhibitory activity to the commonly used antileishmanial drugs included in this study.
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Claims 13
Claim · model-written summary
Wushwush green tea had the highest polyphenol content.
Verbatim
e0“Wushwush green tea had the highest content of polyphenol (19.98 ± 1.15 mg gallic acid equivalent /100 g dry leaf weight), catechin (37.06 mg/g) and L-theanine (48.54 mg/g but the lowest caffeine content).”
Claim · model-written summary
Wushwush green tea had the highest catechin content.
Verbatim
e0“Wushwush green tea had the highest content of polyphenol (19.98 ± 1.15 mg gallic acid equivalent /100 g dry leaf weight), catechin (37.06 mg/g) and L-theanine (48.54 mg/g but the lowest caffeine content).”
Claim · model-written summary
Wushwush green tea had the highest L-theanine content.
Verbatim
e0“Wushwush green tea had the highest content of polyphenol (19.98 ± 1.15 mg gallic acid equivalent /100 g dry leaf weight), catechin (37.06 mg/g) and L-theanine (48.54 mg/g but the lowest caffeine content).”
Claim · model-written summary
Wushwush green tea had the lowest caffeine content.
Verbatim
e0“Wushwush green tea had the highest content of polyphenol (19.98 ± 1.15 mg gallic acid equivalent /100 g dry leaf weight), catechin (37.06 mg/g) and L-theanine (48.54 mg/g but the lowest caffeine content).”
Claim · model-written summary
Wushwush green tea exhibited the highest antioxidant activity.
Verbatim
e0“It exhibited the highest antioxidant activity.”
e1“Wushwush green tea had the highest content of polyphenol”
Claim · model-written summary
The authors attributed the highest antioxidant effect of Wushwush green tea to its highest polyphenol content.
Verbatim
e0“The highest antioxidant effect of Wushwush green tea may be attributed to the highest polyphenol content.”
Claim · model-written summary
East African black tea had the lowest L-theanine content.
Verbatim
e0“East African black tea had the lowest L-theanine (20.72 mg/g) and antioxidant activity but the highest caffeine (16.60 mg/g) content.”
Claim · model-written summary
East African black tea had the lowest antioxidant activity.
Verbatim
e0“East African black tea had the lowest L-theanine (20.72 mg/g) and antioxidant activity but the highest caffeine (16.60 mg/g) content.”
Claim · model-written summary
East African black tea had the highest caffeine content.
Verbatim
e0“East African black tea had the lowest L-theanine (20.72 mg/g) and antioxidant activity but the highest caffeine (16.60 mg/g) content.”
Claim · model-written summary
Wushwush green tea slightly inhibited L. aethiopica.
Verbatim
e0“Wushwush green tea showed slight inhibitory effect on L. aethiopica”
Claim · model-written summary
Gumero, East Africa, and Wushwush black tea extracts exhibited no antileishmanial activity.
Verbatim
e0“lack tea extracts (Gumero, East Africa and Wushwush) exhibited no antileishmanial activity”
e1“Wushwush green tea showed slight inhibitory effect on L. aethiopica”
Claim · model-written summary
Wushwush green tea showed no synergistic or antagonistic effect on the antileishmanial drugs.
Verbatim
e0“Wushwush green tea did not show any synergistic or antagonistic effect on the antileishmanial drugs used in this study”
Claim · model-written summary
Gumero, East Africa, and Wushwush black tea extracts showed dose dependent inhibition of the antileishmanial drugs.
Verbatim
e0“Gumero, East Africa and Wushwush black tea extracts exhibited dose dependant inhibitory activity to the commonly used antileishmanial drugs included in this study.”