Abstract
In total, 150 protein extracts from 94 different basidiomycete and ascomycete wild mushroom species were tested for antibacterial activity against the quarantine plant-pathogen bacterium Ralstonia solanacearum. In in vitro microtiter plate assays, 15 extracts with moderate to high antibacterial activities were identified: 11 completely inhibited bacterial growth and 4 showed partial inhibition. Of these 15 extracts, 5 were further tested and 3 extracts slowed disease progression and reduced disease severity in artificially inoculated tomato and potato plants. However, the in vitro activities of the extracts did not always correlate with their in vivo activities, which emphasizes the importance of performing early screening tests also in vivo. Testing of selected extracts against 12 R. solanacearum strains identified 6 with potential for broader applicability. Further analysis of extracts from Amanita phalloides and Clitocybe geotropa showed that the active substances are proteins with an approximate size of 180 kDa. To our knowledge, this is the first in vitro and in vivo study that demonstrates that mushroom protein extracts can be promising for treatment of bacterial wilt caused by R. solanacearum.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 6
Claim · model-written summary
Fifteen mushroom extracts inhibited Ralstonia growth in vitro: 11 completely and four partially.
- Interactor
- Ralstonia solanacearum
Ralstonia solanacearume1pathogene2 - Outcome
- antibacterial activitiese0
- Value
- 15 extractse0
Not reportedTaxon
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“15 extracts with moderate to high antibacterial activities were identified: 11 completely inhibited bacterial growth and 4 showed partial inhibition”
e1“Ralstonia solanacearum”
e2“pathogen”
Claim · model-written summary
Three mushroom extracts slowed bacterial wilt progression in inoculated tomato plants.
- Taxon
- tomato
Solanum lycopersicume0 - Treatment
- 3 extractse0
- Interactor
- Ralstonia solanacearumRalstonia solanacearume1pathogene2
- Outcome
- disease progressione0
- Direction
- slowede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“3 extracts slowed disease progression and reduced disease severity in artificially inoculated tomato and potato plants”
e1“Ralstonia solanacearum”
e2“pathogen”
Claim · model-written summary
Three mushroom extracts reduced bacterial wilt severity in inoculated potato plants.
- Taxon
- potato
Solanum tuberosume0 - Treatment
- 3 extractse0
- Interactor
- Ralstonia solanacearumRalstonia solanacearume1pathogene2
- Outcome
- disease severitye0
- Direction
- reducede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“3 extracts slowed disease progression and reduced disease severity in artificially inoculated tomato and potato plants”
e1“Ralstonia solanacearum”
e2“pathogen”
Claim · model-written summary
In vitro extract activity did not always correlate with activity in plants.
Not reportedTaxon
Verbatim
e0“the in vitro activities of the extracts did not always correlate with their in vivo activities”
Claim · model-written summary
Six extracts showed potential activity across 12 Ralstonia strains.
- Interactor
- R. solanacearumRalstonia solanacearume0pathogen
- Outcome
- potential for broader applicabilitye0
- Value
- 6e0
Not reportedTaxon
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Testing of selected extracts against 12 R. solanacearum strains identified 6 with potential for broader applicability”
Claim · model-written summary
The active substances in Amanita phalloides extracts were approximately 180 kDa proteins.
Not reportedTaxon
Verbatim
e0“extracts from Amanita phalloides and Clitocybe geotropa showed that the active substances are proteins with an approximate size of 180 kDa”
The same questions in other papers
botanical · Ralstonia solanacearum · Solanum lycopersicum (tomato)Positive and negative results
27 papers in the same direction as this paper · 3 in the opposite direction
- positive
- no effect
- negative
27 papers more in this group
See all 31 papers →botanical · Ralstonia solanacearum · Solanum tuberosum (potato)Results agree
7 papers in the same direction as this paper
- positive
- positive
- positive
4 papers more in this group
See all 8 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.