Abstract
SUMMARY: Culture filtrates of Trichothecium roseum contain two heat-stable substances that inhibit infection with plant viruses. One is trichothecin, an antifungal substance with the molecular formula C19H24O5; it sometimes visibly damages bean leaves. The other was isolated as a polysaccharide, [α] D 19° = −33° it contains 1·1–1·4% nitrogen, yields 60–70% reducing sugars (as glucose) on acidic hydrolysis, and the predominant (45%) component sugar is d-galactose. The polysaccharide does not combine with tobacco mosaic virus in vitro. The extent to which infection is inhibited depends on the species of the host plant but not on the identity of the virus. Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa, whereas the polysaccharide and two derivatives of trichothecin (trichothecolone and acetyltrichothecolone) affect N. glutinosa more than beans. Trichothecin inhibits infection when sprayed over leaves a day after they have been inoculated with viruses, but is ineffective when applied 2 days before. The polysaccharide inhibits when sprayed over leaves before inoculation but not after. It is suggested that inhibitors act by temporarily altering the metabolism of leaf cells so that introduced virus particles cannot multiply and are inactivated.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 12
Claim · model-written summary
Culture filtrates of Trichothecium roseum contain two heat-stable substances that inhibit infection with plant viruses.
- Taxon
- beanse2
- Treatment
- Culture filtrates of Trichothecium roseume1
- Interactor
- plant virusese1pathogen
- Outcome
- infectione1
- Direction
- inhibite1
Not reportedComparator
Verbatim
e1“Culture filtrates of Trichothecium roseum contain two heat-stable substances that inhibit infection with plant viruses”
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
Claim · model-written summary
Trichothecin inhibits infection when sprayed over leaves a day after inoculation with viruses.
Not reportedComparator
Verbatim
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
e3“Trichothecin inhibits infection when sprayed over leaves a day after they have been inoculated with viruses”
Claim · model-written summary
Trichothecin is ineffective when applied 2 days before inoculation.
- Taxon
- beanse2
- Treatment
- Trichothecine3
- Outcome
- infectione3
- Direction
- ineffectivee4
- Qualifier
- applied 2 days beforee4
Not reportedComparator
Verbatim
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
e3“Trichothecin inhibits infection when sprayed over leaves a day after they have been inoculated with viruses”
e4“but is ineffective when applied 2 days before”
Claim · model-written summary
The polysaccharide inhibits infection when sprayed over leaves before inoculation.
- Taxon
- beanse2
- Treatment
- polysaccharidee5
- Interactor
- plant virusese1pathogen
- Outcome
- infectione1
- Direction
- inhibitse5
- Qualifier
- before inoculatione5
Not reportedComparator
Verbatim
e1“Culture filtrates of Trichothecium roseum contain two heat-stable substances that inhibit infection with plant viruses”
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
e5“The polysaccharide inhibits when sprayed over leaves before inoculation but not after”
Claim · model-written summary
The polysaccharide does not inhibit infection when sprayed over leaves after inoculation.
Not reportedComparatorDirection
Verbatim
e1“Culture filtrates of Trichothecium roseum contain two heat-stable substances that inhibit infection with plant viruses”
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
e5“The polysaccharide inhibits when sprayed over leaves before inoculation but not after”
Claim · model-written summary
The polysaccharide does not combine with tobacco mosaic virus in vitro.
- Taxon
- beanse2
- Treatment
- polysaccharidee6
- Interactor
- tobacco mosaic virus
Tobacco mosaic viruse6pathogen - Outcome
- combine with tobacco mosaic viruse6
- Qualifier
- in vitroe6
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
e6“The polysaccharide does not combine with tobacco mosaic virus in vitro”
Claim · model-written summary
The extent of infection inhibition depends on the host plant species but not on the identity of the virus.
Verbatim
e7“The extent to which infection is inhibited depends on the species of the host plant but not on the identity of the virus”
Claim · model-written summary
Trichothecin is relatively more effective against infection in beans than in Nicotiana glutinosa.
Verbatim
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
Claim · model-written summary
The polysaccharide and two trichothecin derivatives affect Nicotiana glutinosa more than beans.
- Taxon
- Nicotiana glutinosa
Nicotiana glutinosae2 - Treatment
- the polysaccharide and two derivatives of trichothecine2
- Outcome
- affecte2
- Direction
- moree2
- Comparator
- beanse2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa, whereas the polysaccharide and two derivatives of trichothecin (trichothecolone and acetyltrichothecolone) affect N. glutinosa more than beans”
Claim · model-written summary
The predominant component sugar of the polysaccharide is d-galactose, at 45%.
Verbatim
e0“it contains 1·1–1·4% nitrogen, yields 60–70% reducing sugars (as glucose) on acidic hydrolysis, and the predominant (45%) component sugar is d-galactose”
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
Claim · model-written summary
The polysaccharide contains 1·1–1·4% nitrogen.
Verbatim
e0“it contains 1·1–1·4% nitrogen, yields 60–70% reducing sugars (as glucose) on acidic hydrolysis, and the predominant (45%) component sugar is d-galactose”
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
Claim · model-written summary
The polysaccharide yields 60–70% reducing sugars on acidic hydrolysis.
Verbatim
e0“it contains 1·1–1·4% nitrogen, yields 60–70% reducing sugars (as glucose) on acidic hydrolysis, and the predominant (45%) component sugar is d-galactose”
e2“Trichothecin, like ribonuclease, is relatively more effective with beans than with Nicotiana glutinosa”
The same questions in other papers
trichothecin · disease · Phaseolus vulgaris (common bean)Positive and negative results
1 in the opposite direction
- positive
polysaccharide · disease · Phaseolus vulgaris (common bean)Results agree
2 papers in the same direction as this paper
- positive
- positive
pathogen product · disease · Phaseolus vulgaris (common bean)Positive and negative results
3 papers in the same direction as this paper · 1 in the opposite direction
- negative
- positive
- positive
1 paper more in this group
See all 5 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.