Abstract
To avoid zinc (Zn) toxicity, plants have developed a Zn homeostasis mechanism to cope with Zn excess in the surrounding soil. In this report, we uncovered the difference of a cross-homeostasis system between iron (Fe) and Zn in dealing with Zn excess in the Zn hyperaccumulator Arabidopsis halleri ssp. gemmifera and nonhyperaccumulator Arabidopsis thaliana. Arabidopsis halleri shows low expression of the Fe acquisition and deficiency response-related genes IRT1 and IRT2 compared with A. thaliana. In A. thaliana, lowering the expression of IRT1 and IRT2 through the addition of excess Fe to the medium increases Zn tolerance. Excess Zn induces significant Fe deficiency in A. thaliana and reduces Fe accumulation in shoots. By contrast, the accumulation of Fe in shoots of A. halleri was stable under various Zn treatments. Root ferric chelate reductase (FRO) activity and expression of FIT are low in A. halleri compared with A. thaliana. Overexpressing a ZIP family member IRT3 in irt1-1, rescues the Fe-deficient phenotype. A fine-tuned Fe homeostasis mechanism in A. halleri maintains optimum Fe level by Zn-regulated ZIP transporters and prevents high Zn uptake through Fe-regulated metal transporters, and in part be responsible for Zn tolerance.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 9
Claim · model-written summary
A. halleri has lower IRT1 and IRT2 expression than A. thaliana.
- Taxon
- Arabidopsis halleri
_IMG_7443.JPG?width=60)
Arabidopsis hallerie0 - Gene
- IRT1 and IRT2e0
- Outcome
- low expressione0
- Comparator
- A. thalianae0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_IMG_7443.JPG?width=500)
Verbatim
e0“Arabidopsis halleri shows low expression of the Fe acquisition and deficiency response-related genes IRT1 and IRT2 compared with A. thaliana.”
Claim · model-written summary
Excess Fe lowered IRT1 and IRT2 expression and increased zinc tolerance in A. thaliana.
- Taxon
- A. thaliana
Arabidopsis thalianae0 - Treatment
- addition of excess Fee0
- Gene
- IRT1 and IRT2e0
- Outcome
- Zn tolerancee0
- Direction
- increasese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In A. thaliana, lowering the expression of IRT1 and IRT2 through the addition of excess Fe to the medium increases Zn tolerance.”
Claim · model-written summary
Excess zinc induced significant iron deficiency in A. thaliana.
- Taxon
- A. thalianaArabidopsis thalianae0
- Treatment
- Excess Zne0
- Outcome
- Fe deficiencye0
- Direction
- inducese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Excess Zn induces significant Fe deficiency in A. thaliana and reduces Fe accumulation in shoots.”
Claim · model-written summary
Excess zinc reduced shoot iron accumulation in A. thaliana.
- Taxon
- A. thalianaArabidopsis thalianae0
- Treatment
- Excess Zne0
- Outcome
- Fe accumulation in shootse0
- Direction
- reducese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Excess Zn induces significant Fe deficiency in A. thaliana and reduces Fe accumulation in shoots.”
Claim · model-written summary
Shoot iron accumulation in A. halleri was stable across zinc treatments.
- Taxon
- A. halleriArabidopsis hallerie0
- Treatment
- various Zn treatmentse0
- Outcome
- accumulation of Fe in shootse0
- Direction
- stablee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the accumulation of Fe in shoots of A. halleri was stable under various Zn treatments.”
Claim · model-written summary
A. halleri had lower root FRO activity than A. thaliana.
- Taxon
- A. halleriArabidopsis hallerie0
- Gene
- ferric chelate reductase (FRO)e0
- Outcome
- Root ferric chelate reductase (FRO) activitye0
- Direction
- lowe0
- Comparator
- A. thalianae0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Root ferric chelate reductase (FRO) activity and expression of FIT are low in A. halleri compared with A. thaliana.”
Claim · model-written summary
A. halleri had lower FIT expression than A. thaliana.
- Taxon
- A. halleriArabidopsis hallerie0
- Gene
- FITe0
- Outcome
- expression of FITe0
- Direction
- lowe0
- Comparator
- A. thalianae0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Root ferric chelate reductase (FRO) activity and expression of FIT are low in A. halleri compared with A. thaliana.”
Claim · model-written summary
IRT3 overexpression rescued the iron deficient phenotype of irt1-1.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Material
- irt1-1e0
- Treatment
- Overexpressing a ZIP family member IRT3e0
- Gene
- IRT3e0
- Outcome
- Fe-deficient phenotypee0
- Direction
- rescuese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Overexpressing a ZIP family member IRT3 in irt1-1, rescues the Fe-deficient phenotype.”
t0“Arabidopsis thaliana”
Claim · model-written summary
The authors attribute zinc tolerance in A. halleri partly to regulated iron homeostasis and limited zinc uptake.
- Taxon
- A. halleriArabidopsis hallerie0
- Gene
- Zn-regulated ZIP transporterse0
- Outcome
- Zn tolerancee0
- Qualifier
- Fe homeostasis mechanisme0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A fine-tuned Fe homeostasis mechanism in A. halleri maintains optimum Fe level by Zn-regulated ZIP transporters and prevents high Zn uptake through Fe-regulated metal transporters, and in part be responsible for Zn tolerance.”
The same questions in other papers
zinc atom · nutrient: content · Arabidopsis thaliana (thale cress)Positive and negative results
2 in the opposite direction
- positive
- positive
iron atom · disease · Arabidopsis thaliana (thale cress)Results agree
3 papers in the same direction as this paper
- positive
- positive
- positive
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.