Abstract
Germination tests of Striga hermonthica seeds were performed using 11β,13-dihydroparthenolide (DHP), a sesquiterpene lactone from Ambrosia artemisifolia (common ragweed). In each test series aqueous solutions with acetone or methanol were used as negative controls. Test solutions of the strigol analogue 2-methyl-4-((2-oxo-2,3,3a,8b-tetrahydro-4 H -indeno[1,2- b ]furan-3-ylidene)methoxy)but-2-en-4-olide (GR 24) in methanol as carrier system were used as positive controls. A decrease in concentration of DHP from 10 - 3 to 10 - 20 M resulted in several unusual “minima” and “maxima” of stimulatory activities, suggesting that the mode of action of DHP could be hormonal. The crystal structure of DHP was determined by X-ray crystallography, and the use of molecular modeling in predicting the biologically active conformations is proposed. Keywords: Striga hermonthica; Scrophulariaceae; 11β,13-dihydroparthenolide; seed germination; X-ray crystallography; molecular mechanics
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Claims 3
Claim · model-written summary
Decreasing DHP concentration from 10 - 3 to 10 - 20 M produced several minima and maxima in Striga seed germination stimulation.
- Taxon
- Striga hermonthica
Striga hermonthicat0 - Treatment
- DHPe0
- Outcome
- stimulatory activitiese0
- Direction
- “minima” and “maxima”e0
- Qualifier
- 10 - 3 to 10 - 20 Me0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Striga hermonthica”
e0“A decrease in concentration of DHP from 10 - 3 to 10 - 20 M resulted in several unusual “minima” and “maxima” of stimulatory activities”
Claim · model-written summary
The concentration response suggests that DHP may act hormonally in Striga germination.
- Taxon
- Striga hermonthicaStriga hermonthicat0
- Outcome
- mode of action of DHP could be hormonale0
- Qualifier
- hormonale0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Striga hermonthica”
e0“suggesting that the mode of action of DHP could be hormonal”
Claim · model-written summary
The crystal structure of DHP was determined by X-ray crystallography.
- Taxon
- Striga hermonthicaStriga hermonthicat0
- Outcome
- crystal structure of DHPe0
Not reportedComparatorValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Striga hermonthica”
e0“The crystal structure of DHP was determined by X-ray crystallography”