Abstract
DFMO (alpha-DL-difluoromethylornithine), a specific irreversible inhibitor of ornithine decarboxylase (ODC), a polyamine biosynthetic pathway enzyme, strongly inhibits root growth and arbuscular mycorrhizal infection of Pisum sativum (P56 myc+, isogenic mutant of cv. Frisson). This inhibition is reversed when exogenous polyamine (putrescine) is included in the DFMO treatment, showing that the effect of DFMO on arbuscular mycorrhizal infection is indeed due to putrescine limitation and suggesting that ODC may have a role in root growth and mycorrhizal infection. However, treatment with gibberellic acid (GA3) which increased root titers of polyamines strongly inhibited arbuscular mycorrhizal development. The possible role of polyamines in the regulation of the development of arbuscular mycorrhizal infection is discussed.
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Claims 5
Claim · model-written summary
DFMO strongly inhibited pea root growth.
- Taxon
- Pisum sativum
Lathyrus oleraceuse0 - Material
- P56 myc+e0
- Treatment
- DFMOe0
- Outcome
- root growthe0
- Direction
- strongly inhibitse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“DFMO (alpha-DL-difluoromethylornithine), a specific irreversible inhibitor of ornithine decarboxylase (ODC), a polyamine biosynthetic pathway enzyme, strongly inhibits root growth and arbuscular mycorrhizal infection of Pisum sativum (P56 myc+, isogenic mutant of cv. Frisson)”
Claim · model-written summary
DFMO strongly inhibited pea arbuscular mycorrhizal infection.
- Taxon
- Pisum sativumLathyrus oleraceuse0
- Material
- P56 myc+e0
- Treatment
- DFMOe0
- Outcome
- arbuscular mycorrhizal infectione0
- Direction
- strongly inhibitse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“DFMO (alpha-DL-difluoromethylornithine), a specific irreversible inhibitor of ornithine decarboxylase (ODC), a polyamine biosynthetic pathway enzyme, strongly inhibits root growth and arbuscular mycorrhizal infection of Pisum sativum (P56 myc+, isogenic mutant of cv. Frisson)”
Claim · model-written summary
Putrescine reversed DFMO inhibition.
- Taxon
- Pisum sativumLathyrus oleraceust0
- Treatment
- exogenous polyamine (putrescine)e0
- Outcome
- inhibitione0
- Direction
- reversede0
- Comparator
- DFMO treatmente0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“This inhibition is reversed when exogenous polyamine (putrescine) is included in the DFMO treatment”
t0“Pisum sativum”
Claim · model-written summary
Gibberellic acid increased root polyamines.
- Taxon
- Pisum sativumLathyrus oleraceust0
- Treatment
- gibberellic acid (GA3)e0
- Outcome
- root titers of polyaminese0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“treatment with gibberellic acid (GA3) which increased root titers of polyamines”
t0“Pisum sativum”
Claim · model-written summary
Gibberellic acid strongly inhibited mycorrhizal development.
- Taxon
- Pisum sativumLathyrus oleraceust0
- Treatment
- gibberellic acid (GA3)e0
- Outcome
- arbuscular mycorrhizal developmente0
- Direction
- strongly inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“treatment with gibberellic acid (GA3) which increased root titers of polyamines strongly inhibited arbuscular mycorrhizal development”
t0“Pisum sativum”
The same questions in other papers
gibberellin A3 · growth · Lathyrus oleraceus (pea)Positive and negative results
2 in the opposite direction
- positive
- positive
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.