Abstract
In the present study, papaya (Carica papaya) seed and edible pulp were carefully separated and then the contents of benzyl isothiocyanate and the corresponding glucosinolate (benzyl glucosinolate, glucotropaeolin) quantified in each part. The papaya seed with myrosinase inactivation contained >1 mmol of benzyl glucosinolate in 100 g of fresh seed. This content is equivalent to that of Karami daikon (the hottest Japanese white radish) or that of cress. The papaya seed extract also showed a very high activity of myrosinase and, without myrosinase inactivation, produced 460 micromol of benzyl isothiocyanate in 100 g of seed. In contrast, papaya pulp contained an undetectable amount of benzyl glucosinolate and showed no significant myrosinase activity. The n-hexane extract of the papaya seed homogenate was highly effective in inhibiting superoxide generation and apoptosis induction in HL-60 cells, the activities of which are comparable to those of authentic benzyl isothiocyanate.
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Claims 7
Claim · model-written summary
Papaya seed with myrosinase inactivation contained more than 1 mmol of benzyl glucosinolate per 100 g fresh seed.
- Taxon
- Carica papaya
Carica papayae0 - Organ / stage
- seede1
- Outcome
- benzyl glucosinolatee1
- Value
- >1 mmole1
- Qualifier
- in 100 g of fresh seede1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e0“papaya (Carica papaya) seed and edible pulp were carefully separated”
e1“The papaya seed with myrosinase inactivation contained >1 mmol of benzyl glucosinolate in 100 g of fresh seed”
Claim · model-written summary
The benzyl glucosinolate content of papaya seed is equivalent to that of Karami daikon.
- Taxon
- Carica papaya
Carica papayae0 - Compound
- benzyl glucosinolatee1
- Outcome
- contente2
- Direction
- equivalente2
- Qualifier
- or that of cresse2
- Comparator
- Karami daikone2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e0“papaya (Carica papaya) seed and edible pulp were carefully separated”
e1“The papaya seed with myrosinase inactivation contained >1 mmol of benzyl glucosinolate in 100 g of fresh seed”
e2“This content is equivalent to that of Karami daikon (the hottest Japanese white radish) or that of cress”
Claim · model-written summary
Papaya seed extract showed very high myrosinase activity.
- Taxon
- Carica papaya
Carica papayae0 - Outcome
- activity of myrosinasee3
- Qualifier
- very highe3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e0“papaya (Carica papaya) seed and edible pulp were carefully separated”
e3“The papaya seed extract also showed a very high activity of myrosinase and, without myrosinase inactivation, produced 460 micromol of benzyl isothiocyanate in 100 g of seed”
Claim · model-written summary
Papaya seed extract without myrosinase inactivation produced 460 micromol of benzyl isothiocyanate per 100 g of seed.
- Taxon
- Carica papaya
Carica papayae0 - Outcome
- benzyl isothiocyanatee3
- Value
- 460 micromole3
- Qualifier
- in 100 g of seede3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e0“papaya (Carica papaya) seed and edible pulp were carefully separated”
e3“The papaya seed extract also showed a very high activity of myrosinase and, without myrosinase inactivation, produced 460 micromol of benzyl isothiocyanate in 100 g of seed”
Claim · model-written summary
Papaya pulp contained an undetectable amount of benzyl glucosinolate.
- Taxon
- papaya
Carica papayae4 - Organ / stage
- pulpe4
- Outcome
- benzyl glucosinolatee4
- Value
- undetectable amounte4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e4“In contrast, papaya pulp contained an undetectable amount of benzyl glucosinolate and showed no significant myrosinase activity”
Claim · model-written summary
Papaya pulp showed no significant myrosinase activity.
- Taxon
- papaya
Carica papayae4 - Organ / stage
- pulpe4
- Outcome
- myrosinase activitye4
- Qualifier
- no significante4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e4“In contrast, papaya pulp contained an undetectable amount of benzyl glucosinolate and showed no significant myrosinase activity”
Claim · model-written summary
The n-hexane extract of papaya seed inhibited superoxide generation and apoptosis induction in HL-60 cells, comparable to authentic benzyl isothiocyanate.
- Taxon
- papaya
Carica papayae5 - Treatment
- n-hexane extract of the papaya seed homogenatee5
- Outcome
- superoxide generation and apoptosis inductione5
- Direction
- inhibitinge5
- Qualifier
- in HL-60 cellse5
- Comparator
- authentic benzyl isothiocyanatee5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_-_DPLA_-_55200ec009622d7d42349f3583df310e.jpg?width=500)
Verbatim
e5“The n-hexane extract of the papaya seed homogenate was highly effective in inhibiting superoxide generation and apoptosis induction in HL-60 cells, the activities of which are comparable to those of authentic benzyl isothiocyanate”
The same questions in other papers
botanical · physiology: oxidative · Carica papaya (papaya)Positive and negative results
1 in the opposite direction
- negative
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.